ATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication.
about
Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progressionGenomic instability in cancer.NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cellsATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase.Cell cycle G2/M arrest through an S phase-dependent mechanism by HIV-1 viral protein R.Replication licensing and the DNA damage checkpoint.Life without geminin.Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplicationHOI-02 induces apoptosis and G2-M arrest in esophageal cancer mediated by ROS"The Octet": Eight Protein Kinases that Control Mammalian DNA Replication.Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation.Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis.Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertilityNeddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.Cdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.Analysis of re-replication from deregulated origin licensing by DNA fiber spreadingRepression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts.Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival.Role of the CRL2(LRR-1) E3 ubiquitin-ligase in the development of the germline in C. elegans.Flipping the switch from g1 to s phase with e3 ubiquitin ligasesThe checkpoint clamp protein Rad9 facilitates DNA-end resection and prevents alternative non-homologous end joining.A role for homologous recombination proteins in cell cycle regulation.Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9.Geminin deletion in pre-meiotic DNA replication stage causes spermatogenesis defect and infertility.Improved Antiviral Activity of a Polyamide Against High-Risk Human Papillomavirus Via N-Terminal Guanidinium Substitution.Influence of nuclear blebs and micronuclei status on the growth kinetics of human mesenchymal stem cells.Epstein-Barr Virus Hijacks DNA Damage Response Transducers to Orchestrate Its Life Cycle.Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells.CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver
P2860
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P2860
ATR pathway is the primary pathway for activating G2/M checkpoint induction after re-replication.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
ATR pathway is the primary pat ...... nduction after re-replication.
@ast
ATR pathway is the primary pat ...... nduction after re-replication.
@en
type
label
ATR pathway is the primary pat ...... nduction after re-replication.
@ast
ATR pathway is the primary pat ...... nduction after re-replication.
@en
prefLabel
ATR pathway is the primary pat ...... nduction after re-replication.
@ast
ATR pathway is the primary pat ...... nduction after re-replication.
@en
P2860
P356
P1476
ATR pathway is the primary pat ...... nduction after re-replication.
@en
P2093
Jie Jessie Lin
P2860
P304
30357-30362
P356
10.1074/JBC.M705178200
P407
P577
2007-08-22T00:00:00Z