Woodchuck post-transcriptional element induces nuclear export of myotonic dystrophy 3' untranslated region transcripts.
about
Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade statusCytoplasmic CUG RNA foci are insufficient to elicit key DM1 features.Efficient hepatocyte engraftment and long-term transgene expression after reversible portal embolization in nonhuman primates.Rational and modular design of potent ligands targeting the RNA that causes myotonic dystrophy 2.Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.Evaluation of combinatorial cis-regulatory elements for stable gene expression in chicken cells.Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive.Prostate cancer-specific and potent antitumor effect of a DD3-controlled oncolytic virus harboring the PTEN gene.Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.Features of modularly assembled compounds that impart bioactivity against an RNA target.Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65Precise small-molecule recognition of a toxic CUG RNA repeat expansion.Rational design of bioactive, modularly assembled aminoglycosides targeting the RNA that causes myotonic dystrophy type 1.Molecular therapy in myotonic dystrophy: focus on RNA gain-of-function.Tackling the pathogenesis of RNA nuclear retention in myotonic dystrophy.Perspectives on gene therapy in myotonic dystrophy type 1.Repeat expansion diseases: when a good RNA turns bad.Improvement of lentiviral transfer vectors using cis-acting regulatory elements for increased gene expression.Improved microRNA suppression by WPRE-linked tough decoy microRNA sponges.Woodchuck hepatitis virus post-transcriptional regulatory element deleted from X protein and promoter sequences enhances retroviral vector titer and expression.mRNA nuclear export and human diseaseCorrection of dystrophia myotonica type 1 pre-mRNA transcripts by artificial trans-splicing.
P2860
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P2860
Woodchuck post-transcriptional element induces nuclear export of myotonic dystrophy 3' untranslated region transcripts.
description
2005 nî lūn-bûn
@nan
2005 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Woodchuck post-transcriptional ...... translated region transcripts.
@ast
Woodchuck post-transcriptional ...... translated region transcripts.
@en
type
label
Woodchuck post-transcriptional ...... translated region transcripts.
@ast
Woodchuck post-transcriptional ...... translated region transcripts.
@en
prefLabel
Woodchuck post-transcriptional ...... translated region transcripts.
@ast
Woodchuck post-transcriptional ...... translated region transcripts.
@en
P2093
P2860
P356
P1433
P1476
Woodchuck post-transcriptional ...... translated region transcripts.
@en
P2093
James B Uney
Leonidas A Phylactou
Mani S Mahadevan
Mariana L Feldman
Nikolaos P Mastroyiannopoulos
P2860
P304
P356
10.1038/SJ.EMBOR.7400390
P577
2005-05-01T00:00:00Z