Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.
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Role of Marine Natural Products in the Genesis of Antiviral AgentsRecent developments in antiviral agents against enterovirus 71 infectionStructural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic CompoundsEnterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug DesignCrystal Structures of Enterovirus 71 3C Protease Complexed with Rupintrivir Reveal the Roles of Catalytically Important ResiduesBroad-spectrum antivirals against 3C or 3C-like proteases of picornaviruses, noroviruses, and coronaviruses.Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93Rhinovirus genome evolution during experimental human infection.Multiple classes of antiviral agents exhibit in vitro activity against human rhinovirus type CIn vitro resistance study of rupintrivir, a novel inhibitor of human rhinovirus 3C protease.New complete genome sequences of human rhinoviruses shed light on their phylogeny and genomic features.In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease.Cathepsin F cysteine protease of the human liver fluke, Opisthorchis viverrini.Rupintrivir is a promising candidate for treating severe cases of Enterovirus-71 infection.Recent development of 3C and 3CL protease inhibitors for anti-coronavirus and anti-picornavirus drug discovery.Progress in the development of poliovirus antiviral agents and their essential role in reducing risks that threaten eradication.Enterovirus infection in Korean children and anti-enteroviral potential candidate agents.An anti-human ICAM-1 antibody inhibits rhinovirus-induced exacerbations of lung inflammation.Rhinovirus 3C protease facilitates specific nucleoporin cleavage and mislocalisation of nuclear proteins in infected host cells.Benserazide, the first allosteric inhibitor of Coxsackievirus B3 3C protease.Genome-wide diversity and selective pressure in the human rhinovirus.Real-time monitoring of human enterovirus (HEV)-infected cells and anti-HEV 3C protease potency by fluorescence resonance energy transfer.In Vitro Assessment of Combinations of Enterovirus Inhibitors against Enterovirus 71Development of antiviral agents for enteroviruses.Picornaviral 3C protease inhibitors and the dual 3C protease/coronaviral 3C-like protease inhibitors.Per aspera ad astra: application of Simplex QSAR approach in antiviral research.Risks associated with the use of live-attenuated vaccine poliovirus strains and the strategies for control and eradication of paralytic poliomyelitis.Structure-based antivirals for emerging and neglected RNA viruses: an emerging field for medicinal chemistry in academia.Cleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases.Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells.RNA-virus proteases counteracting host innate immunity.In Vitro Efficacy of Antiviral Compounds against Enterovirus D68.The enterovirus 3C protease inhibitor SG85 efficiently blocks rhinovirus replication and is not cross-resistant with rupintrivir.Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study.Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death.
P2860
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P2860
Conservation of amino acids in human rhinovirus 3C protease correlates with broad-spectrum antiviral activity of rupintrivir, a novel human rhinovirus 3C protease inhibitor.
description
2005 nî lūn-bûn
@nan
2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
name
Conservation of amino acids in ...... novirus 3C protease inhibitor.
@ast
Conservation of amino acids in ...... novirus 3C protease inhibitor.
@en
type
label
Conservation of amino acids in ...... novirus 3C protease inhibitor.
@ast
Conservation of amino acids in ...... novirus 3C protease inhibitor.
@en
prefLabel
Conservation of amino acids in ...... novirus 3C protease inhibitor.
@ast
Conservation of amino acids in ...... novirus 3C protease inhibitor.
@en
P2093
P2860
P1476
Conservation of amino acids in ...... inovirus 3C protease inhibitor
@en
P2093
A K Patick
D A Matthews
F Maldonado
L S Zalman
M A Brothers
S L Binford
P2860
P304
P356
10.1128/AAC.49.2.619-626.2005
P407
P50
P577
2005-02-01T00:00:00Z