Regulation of macrophage alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein by lipopolysaccharide and interferon-gamma
about
Binding of alpha2ML1 to the low density lipoprotein receptor-related protein 1 (LRP1) reveals a new role for LRP1 in the human epidermisInflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophagesLDL receptor-related protein-1: a regulator of inflammation in atherosclerosis, cancer, and injury to the nervous systemMyeloid cell receptor LRP1/CD91 regulates monocyte recruitment and angiogenesis in tumorsExpression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein is increased in reactive and neoplastic glial cells.Epidermal growth factor and platelet-derived growth factor-BB induce a stable increase in the activity of low density lipoprotein receptor-related protein in vascular smooth muscle cells by altering receptor distribution and recycling.Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin.Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive propertiesInterferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription.A novel role of Sp1 and Sp3 in the interferon-gamma -mediated suppression of macrophage lipoprotein lipase gene transcription.Deficiency of invariant V alpha 14 natural killer T cells decreases atherosclerosis in LDL receptor null miceApplicability and precautions of use of liver injury biomarker FibroTest. A reappraisal at 7 years of ageModulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.Enhanced macrophage resistance to Pseudomonas exotoxin A is correlated with decreased expression of the low-density lipoprotein receptor-related protein.Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesionsReceptors, mediators, and mechanisms involved in bacterial sepsis and septic shock.Thematic review series: The immune system and atherogenesis. Cytokine regulation of macrophage functions in atherogenesis.Expression and regulation of apolipoprotein E receptors in the cells of the central nervous system in culture: A review.LDL receptor-related protein-1 regulates NFκB and microRNA-155 in macrophages to control the inflammatory response.Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptorIFN-gamma potentiates atherosclerosis in ApoE knock-out mice.The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- mice.Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's diseaseLRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways.Regulation of proteolytic activity in tissues.Role of alpha(2)-macroglobulin in fever and cytokine responses induced by lipopolysaccharide in mice.Enhancement of the binding of triglyceride-rich lipoproteins to the very low density lipoprotein receptor by apolipoprotein E and lipoprotein lipase.The activities of LDL Receptor-related Protein-1 (LRP1) compartmentalize into distinct plasma membrane microdomains.Astaxanthin acts via LRP-1 to inhibit inflammation and reverse lipopolysaccharide-induced M1/M2 polarization of microglial cells.Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-/- miceInhibition of platelet-derived growth factor-BB-induced fibroblast proliferation by plasmin-activated alpha 2-macroglobulin is mediated via an alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein-dependent mechanism.Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuroinflammation.Limited mutations in full-length tetrameric human alpha2-macroglobulin abrogate binding of platelet-derived growth factor-BB and transforming growth factor-beta1.LRP-1 Attenuates House Dust Mite-induced Eosinophilic Airway Inflammation by Suppressing Dendritic Cell-mediated Adaptive Immune Responses.A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity.
P2860
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P2860
Regulation of macrophage alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein by lipopolysaccharide and interferon-gamma
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Regulation of macrophage alpha ...... accharide and interferon-gamma
@ast
Regulation of macrophage alpha ...... accharide and interferon-gamma
@en
type
label
Regulation of macrophage alpha ...... accharide and interferon-gamma
@ast
Regulation of macrophage alpha ...... accharide and interferon-gamma
@en
prefLabel
Regulation of macrophage alpha ...... accharide and interferon-gamma
@ast
Regulation of macrophage alpha ...... accharide and interferon-gamma
@en
P2093
P2860
P356
P1476
Regulation of macrophage alpha ...... accharide and interferon-gamma
@en
P2093
E L Kittler
P J Quesenberry
S L Gonias
P2860
P304
P356
10.1172/JCI116283
P407
P577
1993-03-01T00:00:00Z