Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness. - Wikidata - wikimedia - TriplyDB

Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness.

Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness.

http://www.wikidata.org/entity/Q30450036

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Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis Analysis of trafficking, stability and function of human connexin 26 gap junction channels with deafness-causing mutations in the fourth transmembrane helix Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides.PDZD7 and hearing loss: More than just a modifier A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).Hearing in the mouse of Usher Tauroursodeoxycholic acid prevents hearing loss and hair cell death in Cdh23(erl/erl) mice.Usher syndrome: Hearing loss, retinal degeneration and associated abnormalities.Sound strategies for hearing restoration.Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse.Next-Generation Sequencing in Oncology: Genetic Diagnosis, Risk Prediction and Cancer Classification.Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c.Gene Therapy Restores Balance and Auditory Functions in a Mouse Model of Usher Syndrome.SHIELD: an integrative gene expression database for inner ear research.Recognizing the 35th anniversary of the proposal that snRNPs are involved in splicing.Genetics of Hearing Loss: Syndromic Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.Targeting RNA splicing for disease therapy.RNA Interference Prevents Autosomal-Dominant Hearing Loss.Splice-switching antisense oligonucleotides as therapeutic drugs ER stress inhibitor attenuates hearing loss and hair cell death in Cdh23erl/erl mutant mice.Usher protein functions in hair cells and photoreceptors.Progress in gene therapy for neurological disorders.Development of therapeutic splice-switching oligonucleotides.Splicing modulation therapy in the treatment of genetic diseases.Potential treatments for genetic hearing loss in humans: current conundrums.New treatment options for hearing loss.Genetic hearing loss: the journey of discovery to destination - how close are we to therapy?Intravenous rAAV2/9 injection for murine cochlear gene delivery.Identification of Adeno-Associated Viral Vectors That Target Neonatal and Adult Mammalian Inner Ear Cell Subtypes.Non-coding RNAs as drug targets.Gene and cell-based therapies for inherited retinal disorders: An update.Signaling in the Auditory System: Implications in Hair Cell Regeneration and Hearing Function.In vitro and in vivo rescue of aberrant splicing in CEP290-associated LCA by antisense oligonucleotide delivery.Effects of genetic correction on the differentiation of hair cell-like cells from iPSCs with MYO15A mutation.Emerging Gene Therapies for Genetic Hearing Loss.Whole USH2A Gene Sequencing Identifies Several New Deep Intronic Mutations.Splicing: hear and now!Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration Electroretinography Reveals Difference in Cone Function between Syndromic and Nonsyndromic USH2A Patients.

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Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness.

http://www.wikidata.org/entity/Q30450036

description

2013 nî lūn-bûn

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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2013 թվականի փետրվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Rescue of hearing and vestibul ...... mouse model of human deafness.

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Rescue of hearing and vestibul ...... mouse model of human deafness.

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Rescue of hearing and vestibul ...... mouse model of human deafness.

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Rescue of hearing and vestibul ...... mouse model of human deafness.

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Rescue of hearing and vestibul ...... mouse model of human deafness.

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Rescue of hearing and vestibul ...... mouse model of human deafness.

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Nature Medicine

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Rescue of hearing and vestibul ...... mouse model of human deafness.

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Anthony J Hinrich

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Dominik M Duelli

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Francine M Jodelka

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Frank Rigo

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Hamilton E Farris

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Jennifer J Lentz

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Kate E McCaffrey

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Matthew J Spalitta

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Michelle L Hastings

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Nicolas G Bazan

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Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction

A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.

A cochlear frequency-position function for several species--29 years later

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth

Regulated reprogramming in the regeneration of sensory receptor cells.

Linking genes underlying deafness to hair-bundle development and function.

Deafness and retinal degeneration in a novel USH1C knock-in mouse model

Harmonin mutations cause mechanotransduction defects in cochlear hair cells.

A new method for imaging and 3D reconstruction of mammalian cochlea by fluorescent confocal microscopy.

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10.1038/NM.3106

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23380860

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