Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom.
about
Alkaline phosphatase mono- and diesterase reactions: comparative transition state analysisRedesigned and chemically-modified hammerhead ribozymes with improved activity and serum stabilityFunctional identification of catalytic metal ion binding sites within RNA.A new paradigm of DNA synthesis: three-metal-ion catalysis.Comparative Enzymology in the Alkaline Phosphatase Superfamily to Determine the Catalytic Role of an Active-Site Metal IonVersatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine AdductsStructure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESStructure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+cofactorCapture of a third Mg²⁺ is essential for catalyzing DNA synthesisChloroplast ribonuclease P does not utilize the ribozyme-type pre-tRNA cleavage mechanismTerminal deoxynucleotidyl transferase: the story of a misguided DNA polymeraseA ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formationRecent advances in the elucidation of the mechanisms of action of ribozymesSolid support synthesis of all-Rp-oligo(ribonucleoside phosphorothioate)s.Mutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site.Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding.Computer simulations of protein functions: searching for the molecular origin of the replication fidelity of DNA polymerasesRegulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selectionFidelity of Nucleotide Incorporation by the RNA-Dependent RNA Polymerase from Poliovirus.CHARMM force field parameters for simulation of reactive intermediates in native and thio-substituted ribozymesAccurate proton affinity and gas-phase basicity values for molecules important in biocatalysis.An unconventional origin of metal-ion rescue and inhibition in the Tetrahymena group I ribozyme reaction.A kinetic and thermodynamic framework for the Azoarcus group I ribozyme reaction.Use of binding energy by an RNA enzyme for catalysis by positioning and substrate destabilization.Role of a GAG hinge in the nucleotide-induced conformational change governing nucleotide specificity by T7 DNA polymerase.Aqueous synthesis of N,S-dialkylthiophosphoramidates: design, optimisation and application to library construction and antileishmanial testing.Analysis of the cleavage reaction of a trans-acting human hepatitis delta virus ribozyme.Phosphorylating DNA with DNA.Steady-state kinetic mechanism of PDK1.Understanding thio-effects in simple phosphoryl systems: role of solvent effects and nucleophile charge.An important base triple anchors the substrate helix recognition surface within the Tetrahymena ribozyme active site.Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerasesCoupling of fast and slow modes in the reaction pathway of the minimal hammerhead ribozyme cleavage.Observations on catalysis by hammerhead ribozymes are consistent with a two-divalent-metal-ion mechanism.Probing enzyme phosphoester interactions by combining mutagenesis and chemical modification of phosphate ester oxygens.Mechanistic consequences of temperature on DNA polymerization catalyzed by a Y-family DNA polymerase.Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mn2+.Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+.The mechanism of nucleotide incorporation by human DNA polymerase eta differs from that of the yeast enzyme.
P2860
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P2860
Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom.
description
1991 nî lūn-bûn
@nan
1991 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Ribozyme-catalyzed and nonenzy ...... idging phosphoryl oxygen atom.
@ast
Ribozyme-catalyzed and nonenzy ...... idging phosphoryl oxygen atom.
@en
type
label
Ribozyme-catalyzed and nonenzy ...... idging phosphoryl oxygen atom.
@ast
Ribozyme-catalyzed and nonenzy ...... idging phosphoryl oxygen atom.
@en
prefLabel
Ribozyme-catalyzed and nonenzy ...... idging phosphoryl oxygen atom.
@ast
Ribozyme-catalyzed and nonenzy ...... idging phosphoryl oxygen atom.
@en
P2093
P356
P1433
P1476
Ribozyme-catalyzed and nonenzy ...... idging phosphoryl oxygen atom.
@en
P2093
Herschlag D
Piccirilli JA
P304
P356
10.1021/BI00234A003
P407
P577
1991-05-01T00:00:00Z