Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins.
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The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcriptionDifferential estradiol and selective estrogen receptor modulator (SERM) regulation of Keratin 13 gene expression and its underlying mechanism in breast cancer cellsImportance of sex to pain and its amelioration; relevance of spinal estrogens and its membrane receptorsAndrogen regulation of the androgen receptor coregulators.Membrane estrogen receptors activate metabotropic glutamate receptors to influence nervous system physiology.Membrane-localised oestrogen receptor alpha and beta influence neuronal activity through activation of metabotropic glutamate receptors.Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α.Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).Steroid receptor coactivators, HER-2 and HER-3 expression is stimulated by tamoxifen treatment in DMBA-induced breast cancer.Nuclear receptor modulation--role of coregulators in selective estrogen receptor modulator (SERM) actions.Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor.Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapySmall molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1.Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover.The function of steroid receptor coactivator-1 in normal tissues and cancerThe molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy.Modelling the glucocorticoid receptor and producing therapeutic agents with anti-inflammatory effects but reduced side-effects.Unique roles of p160 coactivators for regulation of breast cancer cell proliferation and estrogen receptor-alpha transcriptional activity.Membrane estrogen receptors acting through metabotropic glutamate receptors: an emerging mechanism of estrogen action in brainPotential of selective estrogen receptor modulators as treatments and preventives of breast cancer.Interactions of methoxyacetic acid with androgen receptor.Interference of pollutants with PPARs: endocrine disruption meets metabolism.Coactivator AIB1 links estrogen receptor transcriptional activity and stability.Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1Estrogenic endocrine-disrupting chemicals: molecular mechanisms of actions on putative human diseases.Plumbagin Enhances Tamoxifen Sensitivity and Inhibits Tumor Invasion in Endocrine Resistant Breast Cancer through EMT Regulation.Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1.ERasing breast cancer resistance through the kinome.
P2860
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P2860
Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins.
description
2004 nî lūn-bûn
@nan
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Selective estrogen receptor mo ...... nd SRC-3 coactivator proteins.
@ast
Selective estrogen receptor mo ...... nd SRC-3 coactivator proteins.
@en
type
label
Selective estrogen receptor mo ...... nd SRC-3 coactivator proteins.
@ast
Selective estrogen receptor mo ...... nd SRC-3 coactivator proteins.
@en
prefLabel
Selective estrogen receptor mo ...... nd SRC-3 coactivator proteins.
@ast
Selective estrogen receptor mo ...... nd SRC-3 coactivator proteins.
@en
P2860
P1476
Selective estrogen receptor mo ...... nd SRC-3 coactivator proteins.
@en
P2093
David M Lonard
Sophia Y Tsai
P2860
P356
10.1128/MCB.24.1.14-24.2004
P407
P577
2004-01-01T00:00:00Z