New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing.
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Characterization of an authentic intermediate in the self-splicing process of ribosomal precursor RNA in macronuclei of Tetrahymena thermophilaA peripheral element assembles the compact core structure essential for group I intron self-splicing.Solution structure of an RNA fragment with the P7/P9.0 region and the 3'-terminal guanosine of the tetrahymena group I intronRNA circularization strategies in vivo and in vitroEvolution of RNA-protein interactions: non-specific binding led to RNA splicing activity of fungal mitochondrial tyrosyl-tRNA synthetasesLong-term evolution of the S788 fungal nuclear small subunit rRNA group I intronsRecent advances in the elucidation of the mechanisms of action of ribozymesEffects of substrate structure on the kinetics of circle opening reactions of the self-splicing intervening sequence from Tetrahymena thermophila: evidence for substrate and Mg2+ binding interactionsMutations at the guanosine-binding site of the Tetrahymena ribozyme also affect site-specific hydrolysis.A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification.Folding of group I introns from bacteriophage T4 involves internalization of the catalytic core.Toward predicting self-splicing and protein-facilitated splicing of group I introns.A self-splicing group I intron in the nuclear pre-rRNA of the green alga, Ankistrodesmus stipitatus.A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicingThe conserved U.G pair in the 5' splice site duplex of a group I intron is required in the first but not the second step of self-splicing.A second catalytic metal ion in group I ribozyme.Splicing of COB intron 5 requires pairing between the internal guide sequence and both flanking exons.Structure of the catalytic core of the Tetrahymena ribozyme as indicated by reactive abbreviated forms of the moleculeSelection of novel forms of a functional domain within the Tetrahymena ribozyme.Mutational evidence for competition between the P1 and the P10 helices of a mitochondrial group I intron.Synthesis of circular RNA in bacteria and yeast using RNA cyclase ribozymes derived from a group I intron of phage T4.Computational prediction of efficient splice sites for trans-splicing ribozymes.A novel technique for the rapid preparation of mutant RNAsA phosphorothioate at the 3' splice-site inhibits the second splicing step in a group I intron.Catalytic activity is retained in the Tetrahymena group I intron despite removal of the large extension of element P5.Two guanosine binding sites exist in group I self-splicing IVS RNAs.Reactivity of modified ribose moieties of guanosine: new cleavage reactions mediated by the IVS of Tetrahymena precursor rRNA.Cotranscriptional splicing of a group I intron is facilitated by the Cbp2 protein.mRNA-decapping enzyme from Saccharomyces cerevisiae: purification and unique specificity for long RNA chainsAutocatalytic activities of intron 5 of the cob gene of yeast mitochondria.A region of group I introns that contains universally conserved residues but is not essential for self-splicingReconstitution of a group I intron self-splicing reaction with an activator RNA.Two mitochondrial group I introns in a metazoan, the sea anemone Metridium senile: one intron contains genes for subunits 1 and 3 of NADH dehydrogenase.Evolution of compensatory substitutions through G.U intermediate state in Drosophila rRNA.Specificity from steric restrictions in the guanosine binding pocket of a group I ribozyme.Isoalloxazine derivatives promote photocleavage of natural RNAs at G.U base pairs embedded within helicesFunctional repair of a mutant chloride channel using a trans-splicing ribozymeBidirectional effectors of a group I intron ribozyme.In vitro self-splicing reactions of the chloroplast group I intron Cr.LSU from Chlamydomonas reinhardtii and in vivo manipulation via gene-replacement.The rate and specificity of a group I ribozyme are inversely affected by choice of monovalent salt.
P2860
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P2860
New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing.
description
1986 nî lūn-bûn
@nan
1986 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
New reactions of the ribosomal ...... he mechanism of self-splicing.
@ast
New reactions of the ribosomal ...... he mechanism of self-splicing.
@en
type
label
New reactions of the ribosomal ...... he mechanism of self-splicing.
@ast
New reactions of the ribosomal ...... he mechanism of self-splicing.
@en
prefLabel
New reactions of the ribosomal ...... he mechanism of self-splicing.
@ast
New reactions of the ribosomal ...... he mechanism of self-splicing.
@en
P2093
P1476
New reactions of the ribosomal ...... he mechanism of self-splicing.
@en
P2093
P304
P356
10.1016/0022-2836(86)90387-6
P407
P577
1986-05-01T00:00:00Z