One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity.
about
Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decayProspects for nucleic acid-based therapeutics against hepatitis C virusA relaxed active site after exon ligation by the group I intronCBP2 protein promotes in vitro excision of a yeast mitochondrial group I intron.The mobile group I intron 3 alpha of the yeast mitochondrial COXI gene encodes a 35-kDa processed protein that is an endonuclease but not a maturase.MSS18, a yeast nuclear gene involved in the splicing of intron aI5 beta of the mitochondrial cox1 transcript.In vivo selection of better self-splicing introns in Escherichia coli: the role of the P1 extension helix of the Tetrahymena intron.A hammerhead ribozyme allows synthesis of a new form of the Tetrahymena ribozyme homogeneous in length with a 3' end blocked for transesterification.A self-splicing group I intron in the nuclear pre-rRNA of the green alga, Ankistrodesmus stipitatus.Direct measurement of oligonucleotide substrate binding to wild-type and mutant ribozymes from Tetrahymena.Alteration of substrate specificity for the endoribonucleolytic cleavage of RNA by the Tetrahymena ribozyme.A Tetrahymena intron nucleotide connected to the GTP/arginine siteA conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicingThe conserved U.G pair in the 5' splice site duplex of a group I intron is required in the first but not the second step of self-splicing.Three-dimensional model of the active site of the self-splicing rRNA precursor of TetrahymenaStructural conventions for group I intronsTranslocation of an RNA duplex on a ribozyme.Minor groove recognition of the conserved G.U pair at the Tetrahymena ribozyme reaction site.Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intronSplicing of COB intron 5 requires pairing between the internal guide sequence and both flanking exons.Evaluating group I intron catalytic efficiency in mammalian cells.RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.Sequence specificity of in vivo reverse splicing of the Tetrahymena group I intronRefolding of rRNA exons enhances dissociation of the Tetrahymena intronEfficient and specific repair of sickle beta-globin RNA by trans-splicing ribozymes.Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells.The Cbp2 protein suppresses splice site mutations in a group I intronDesign and Experimental Evolution of trans-Splicing Group I Intron Ribozymes.Reverse splicing of the Tetrahymena IVS: evidence for multiple reaction sites in the 23S rRNA.Structure of the catalytic core of the Tetrahymena ribozyme as indicated by reactive abbreviated forms of the moleculeMutational evidence for competition between the P1 and the P10 helices of a mitochondrial group I intron.Spliceozymes: ribozymes that remove introns from pre-mRNAs in trans.Engineered ribozymes as molecular tools for site-specific alteration of RNA sequence.Computational prediction of efficient splice sites for trans-splicing ribozymes.Thermodynamics and kinetics for base-pair opening in the P1 duplex of the Tetrahymena group I ribozymeTwo guanosine binding sites exist in group I self-splicing IVS RNAs.Tetrahymena australis (Protozoa, Ciliophora): A Well-Known But "Non-Existing" Taxon - Consideration of Its Identification, Definition and Systematic Position.Reactivity of modified ribose moieties of guanosine: new cleavage reactions mediated by the IVS of Tetrahymena precursor rRNA.Cooperative and anticooperative binding to a ribozyme.An alternative helix in the 26S rRNA promotes excision and integration of the Tetrahymena intervening sequence.
P2860
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P2860
One binding site determines sequence specificity of Tetrahymena pre-rRNA self-splicing, trans-splicing, and RNA enzyme activity.
description
1986 nî lūn-bûn
@nan
1986 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
One binding site determines se ...... cing, and RNA enzyme activity.
@ast
One binding site determines se ...... cing, and RNA enzyme activity.
@en
type
label
One binding site determines se ...... cing, and RNA enzyme activity.
@ast
One binding site determines se ...... cing, and RNA enzyme activity.
@en
prefLabel
One binding site determines se ...... cing, and RNA enzyme activity.
@ast
One binding site determines se ...... cing, and RNA enzyme activity.
@en
P1433
P1476
One binding site determines se ...... cing, and RNA enzyme activity.
@en
P304
P356
10.1016/0092-8674(86)90443-5
P407
P577
1986-10-01T00:00:00Z