Inactivation of the small GTPase Rho disrupts cellular attachment and induces adhesion-dependent and adhesion-independent apoptosis.
about
Distinct biological activities of C3 and ADP-ribosyltransferase-deficient C3-E174QThe MEK1 scaffolding protein MP1 regulates cell spreading by integrating PAK1 and Rho signals.RhoB alteration is necessary for apoptotic and antineoplastic responses to farnesyltransferase inhibitorsRho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous systemRac1 and RhoG promote cell survival by the activation of PI3K and Akt, independently of their ability to stimulate JNK and NF-kappaBRas-GTPase activating protein inhibition specifically induces apoptosis of tumour cells.Human RhoA/RhoGDI complex expressed in yeast: GTP exchange is sufficient for translocation of RhoA to liposomes.Activation-dependent degradation of protein kinase C eta.Primary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signalingDirectional shear flow and Rho activation prevent the endothelial cell apoptosis induced by micropatterned anisotropic geometry.RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.Rho protein inactivation induced apoptosis of cultured human endothelial cells.Primary human colonic myofibroblasts are resistant to Clostridium difficile toxin A-induced, but not toxin B-induced, cell death.RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signalRho-independent stimulation of axon outgrowth and activation of the ERK and Akt signaling pathways by C3 transferase in sensory neuronsVibrio parahaemolyticus inhibition of Rho family GTPase activation requires a functional chromosome I type III secretion systemArhGAP15, a Rac-specific GTPase-activating protein, plays a dual role in inhibiting small GTPase signalingThe role of the RhoA/Rho kinase pathway in angiogenesis and its potential value in prostate cancer (Review).C3 toxin activates the stress signaling pathways, JNK and p38, but antagonizes the activation of AP-1 in rat-1 cells.SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signalingDifference in the cytotoxic effects of toxin B from Clostridium difficile strain VPI 10463 and toxin B from variant Clostridium difficile strain 1470.Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function.The Haemophilus ducreyi cytolethal distending toxin induces DNA double-strand breaks and promotes ATM-dependent activation of RhoA.Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.Rho family proteins modulate rapid apoptosis induced by cytotoxic T lymphocytes and Fas.Effect of Rho and ADP-ribosylation factor GTPases on phospholipase D activity in intact human adenocarcinoma A549 cells.Possible involvement of caspase-like family in maintenance of cytoskeleton integrity.Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells.Involvement of Rho/Rho kinase pathway in regulation of apoptosis in rat hepatic stellate cells.Characterization of RhoA-mediated chemoresistance in gastric cancer cells.
P2860
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P2860
Inactivation of the small GTPase Rho disrupts cellular attachment and induces adhesion-dependent and adhesion-independent apoptosis.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Inactivation of the small GTPa ...... dhesion-independent apoptosis.
@ast
Inactivation of the small GTPa ...... dhesion-independent apoptosis.
@en
type
label
Inactivation of the small GTPa ...... dhesion-independent apoptosis.
@ast
Inactivation of the small GTPa ...... dhesion-independent apoptosis.
@en
prefLabel
Inactivation of the small GTPa ...... dhesion-independent apoptosis.
@ast
Inactivation of the small GTPa ...... dhesion-independent apoptosis.
@en
P2093
P356
P1433
P1476
Inactivation of the small GTPa ...... dhesion-independent apoptosis.
@en
P2093
P2888
P304
P356
10.1038/SJ.ONC.1201396
P407
P577
1997-10-01T00:00:00Z
P5875
P6179
1033831396