Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP. - Wikidata - wikimedia - TriplyDB

Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.

Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.

http://www.wikidata.org/entity/Q30477201

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A structural and mutagenic blueprint for molecular recognition of strychnine and d-tubocurarine by different cys-loop receptors End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease Mammalian nicotinic acetylcholine receptors: from structure to function Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity α-RgIA, a Novel Conotoxin That Blocks the α9α10 nAChR: Structure and Identification of Key Receptor-Binding Residues Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein Intersubunit Bridge Formation Governs Agonist Efficacy at Nicotinic Acetylcholine 4 2 Receptors: UNIQUE ROLE OF HALOGEN BONDING REVEALED Assembly of a π–π stack of ligands in the binding site of an acetylcholine-binding protein Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors through Study of Ligand Complexes with Acetylcholine-binding Protein Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides Residues Responsible for the Selectivity of α-Conotoxins for Ac-AChBP or nAChRs Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations A Structural Model of the Human α7 Nicotinic Receptor in an Open Conformation Escherichia coli Protein Expression System for Acetylcholine Binding Proteins (AChBPs)A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists.The neurobiologist's guide to structural biology: a primer on why macromolecular structure matters and how to evaluate structural data.New tools for targeted disruption of cholinergic synaptic transmission in Drosophila melanogaster.A virtual screening study of the acetylcholine binding protein using a relaxed-complex approach Alpha-conotoxins as pharmacological probes of nicotinic acetylcholine receptors.Conotoxins targeting nicotinic acetylcholine receptors: an overview Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor.Use of venom peptides to probe ion channel structure and function.A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA.Efficient expression of acetylcholine-binding protein from Aplysia californica in Bac-to-Bac system Molecular dynamics simulations and drug discovery Tarantula toxins interacting with voltage sensors in potassium channels.Structural answers and persistent questions about how nicotinic receptors work.Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.Conformational flexibility in the binding surface of the potassium channel blocker ShK.Conformational changes in acetylcholine binding protein investigated by temperature accelerated molecular dynamics.Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins.Molecular basis for the differential sensitivity of rat and human α9α10 nAChRs to α-conotoxin RgIA.Atypical nicotinic agonist bound conformations conferring subtype selectivity.Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR.Spontaneous conformational change and toxin binding in alpha7 acetylcholine receptor: insight into channel activation and inhibition Muscle and neuronal nicotinic acetylcholine receptors. Structure, function and pathogenicity.

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P2860

Structural determinants of selective alpha-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP.

http://www.wikidata.org/entity/Q30477201

description

2006 nî lūn-bûn

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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի փետրվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Structural determinants of sel ...... holine receptor homolog AChBP.

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Structural determinants of sel ...... holine receptor homolog AChBP.

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Structural determinants of sel ...... holine receptor homolog AChBP.

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Structural determinants of sel ...... holine receptor homolog AChBP.

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Structural determinants of sel ...... holine receptor homolog AChBP.

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Proceedings of the National Academy of Sciences of the United States of America

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Structural determinants of sel ...... holine receptor homolog AChBP.

@en

P2093

August B Smit

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Chris Ulens

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Daniel Bertrand

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Patrick H Celie

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Ronald C Hogg

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Titia K Sixma

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Victor Tsetlin

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P2860

NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors

Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance

Minimal conformation of the alpha-conotoxin ImI for the alpha7 neuronal nicotinic acetylcholine receptor recognition: correlated CD, NMR and binding studies

Structure-activity relationships in a peptidic alpha7 nicotinic acetylcholine receptor antagonist

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

NMR spatial structure of alpha-conotoxin ImI reveals a common scaffold in snail and snake toxins recognizing neuronal nicotinic acetylcholine receptors

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

Coot: model-building tools for molecular graphics

Automated protein model building combined with iterative structure refinement

Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

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10

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103

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