beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity. - Wikidata - wikimedia - TriplyDB

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

http://www.wikidata.org/entity/Q30477945

about

The emerging roles of β-arrestins in fibrotic diseases Podocyte endocytosis in the regulation of the glomerular filtration barrier The function of endocytosis in podocytes Membrane trafficking in podocyte health and disease Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization Direct regulation of nephrin tyrosine phosphorylation by Nck adaptor proteins.Nck proteins maintain the adult glomerular filtration barrier.Role of dynamin, synaptojanin, and endophilin in podocyte foot processes.Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release.Podocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis A novel in vivo method to quantify slit diaphragm protein abundance in murine proteinuric kidney disease.Planar cell polarity and the kidney.c-mip impairs podocyte proximal signaling and induces heavy proteinuria Nineteen novel NPHS1 mutations in a worldwide cohort of patients with congenital nephrotic syndrome (CNS)A novel domain regulating degradation of the glomerular slit diaphragm protein podocin in cell culture systems.β-Arrestin-mediated receptor trafficking and signal transduction Prorenin receptor is essential for normal podocyte structure and function Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells.Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor β-Arrestins promote podocyte injury by inhibition of autophagy in diabetic nephropathy.Nephrin deficiency activates NF-kappaB and promotes glomerular injury.Nephrin missense mutations: induction of endoplasmic reticulum stress and cell surface rescue by reduction in chaperone interactions.Angiotensin II increases glomerular permeability by β-arrestin mediated nephrin endocytosis.Endocytic Trafficking at the Mature Podocyte Slit Diaphragm.Immunopathogenesis of idiopathic nephrotic syndrome with relapse.Anion exchanger 1 in red blood cells and kidney: Band 3's in a pod.Tyrosine kinase signaling in kidney glomerular podocytes.Signaling from the podocyte intercellular junction to the actin cytoskeleton.The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.A potential role for mechanical forces in the detachment of podocytes and the progression of CKD.SMILE silencing and PMA activation gene networks in HeLa cells: comparison with kidney transplantation gene networks.Phosphorylation of H2A.XTyr39 positively regulates DNA damage response and is linked to cancer progression.PACSIN2 accelerates nephrin trafficking and is up-regulated in diabetic kidney disease.Mechanical challenges to the glomerular filtration barrier: adaptations and pathway to sclerosis.Podocyte-actin dynamics in health and disease.Phosphorylation of nephrin triggers its internalization by raft-mediated endocytosis.Notch promotes dynamin-dependent endocytosis of nephrin Phosphorylated YDXV motifs and Nck SH2/SH3 adaptors act cooperatively to induce actin reorganization.Nephrin Tyrosine Phosphorylation Is Required to Stabilize and Restore Podocyte Foot Process Architecture.

P2860

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P2860

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

http://www.wikidata.org/entity/Q30477945

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

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2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

@ast

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

@en

type

label

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

@ast

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

@en

prefLabel

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

@ast

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

@en

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PNAS.0602587103

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.

@en

P2093

Inga Walther

http://www.w3.org/2001/XMLSchema#string

Ivo Quack

http://www.w3.org/2001/XMLSchema#string

L Christian Rump

http://www.w3.org/2001/XMLSchema#string

Lorenz Sellin

http://www.w3.org/2001/XMLSchema#string

Oliver Vonend

http://www.w3.org/2001/XMLSchema#string

Peter Gerke

http://www.w3.org/2001/XMLSchema#string

Thomas Grunwald

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Tobias Vinke

http://www.w3.org/2001/XMLSchema#string

P2860

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

NEPH1 defines a novel family of podocin interacting proteins

Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling

beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

Clustering-induced tyrosine phosphorylation of nephrin by Src family kinases

Homodimerization and heterodimerization of the glomerular podocyte proteins nephrin and NEPH1

Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4

Interaction with podocin facilitates nephrin signaling

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14110-14115

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scholarly article

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10.1073/PNAS.0602587103

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P433

38

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103

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2006-09-12T00:00:00Z

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6821810

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16968782

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1564064

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