Identification of an essential domain in the herpesvirus VP1/2 tegument protein: the carboxy terminus directs incorporation into capsid assemblons
about
The herpesvirus VP1/2 protein is an effector of dynein-mediated capsid transport and neuroinvasion.Conserved Tryptophan Motifs in the Large Tegument Protein pUL36 Are Required for Efficient Secondary Envelopment of Herpes Simplex Virus Capsids.The C terminus of the large tegument protein pUL36 contains multiple capsid binding sites that function differently during assembly and cell entry of herpes simplex virusStructure and capsid association of the herpesvirus large tegument protein UL36.Organization of capsid-associated tegument components in Kaposi's sarcoma-associated herpesvirusA herpesvirus encoded deubiquitinase is a novel neuroinvasive determinantA single mutation responsible for temperature-sensitive entry and assembly defects in the VP1-2 protein of herpes simplex virus.Proteomic characterization of pseudorabies virus extracellular virionsAutocatalytic activity of the ubiquitin-specific protease domain of herpes simplex virus 1 VP1-2.A functional ubiquitin-specific protease embedded in the large tegument protein (ORF64) of murine gammaherpesvirus 68 is active during the course of infectionA Nuclear localization signal in herpesvirus protein VP1-2 is essential for infection via capsid routing to the nuclear pore.Identification of a highly conserved, functional nuclear localization signal within the N-terminal region of herpes simplex virus type 1 VP1-2 tegument protein.Two viral kinases are required for sustained long distance axon transport of a neuroinvasive herpesvirus.Herpes simplex virus 1 ubiquitin-specific protease UL36 inhibits beta interferon production by deubiquitinating TRAF3.Cleavage specificity of the UL48 deubiquitinating protease activity of human cytomegalovirus and the growth of an active-site mutant virus in cultured cells.Mutagenesis of the active-site cysteine in the ubiquitin-specific protease contained in large tegument protein pUL36 of pseudorabies virus impairs viral replication in vitro and neuroinvasion in vivo.Insights into herpesvirus tegument organization from structural analyses of the 970 central residues of HSV-1 UL36 protein.Recovery of an HMWP/hmwBP (pUL48/pUL47) complex from virions of human cytomegalovirus: subunit interactions, oligomer composition, and deubiquitylase activity.Functional analysis of nuclear localization signals in VP1-2 homologues from all herpesvirus subfamiliesNuclear targeting of human cytomegalovirus large tegument protein pUL48 is essential for viral growth.Analysis of the early steps of herpes simplex virus 1 capsid tegumentation.Tsg101 interacts with herpes simplex virus 1 VP1/2 and is a substrate of VP1/2 ubiquitin-specific protease domain activity.Nuclear egress of pseudorabies virus capsids is enhanced by a subspecies of the large tegument protein that is lost upon cytoplasmic maturationRandom transposon-mediated mutagenesis of the essential large tegument protein pUL36 of pseudorabies virus.The UL25 gene product of herpes simplex virus type 1 is involved in uncoating of the viral genomeIntracellular localization of the pseudorabies virus large tegument protein pUL36.Identification of functional domains within the essential large tegument protein pUL36 of pseudorabies virus.The capsid and tegument of the alphaherpesviruses are linked by an interaction between the UL25 and VP1/2 proteins.Herpesvirus Nuclear Egress.The herpes simplex virus 1 UL36USP deubiquitinase suppresses DNA repair in host cells via deubiquitination of proliferating cell nuclear antigen.Herpes Simplex Virus Capsid Localization to ESCRT-VPS4 Complexes in the Presence and Absence of the Large Tegument Protein UL36p.Kaposi's sarcoma-associated herpesvirus encodes a viral deubiquitinase.Functional Interaction Between the ESCRT-I Component TSG101 and the HSV-1 Tegument Ubiquitin Specific Protease.Structure of the herpes simplex virus 1 capsid with associated tegument protein complexes.
P2860
Q28116141-B71275A3-5BBB-4A81-BD79-16E621628550Q30355292-86D8C0C3-D6F3-42F2-AA6F-04BDB36AC7DFQ30424771-DBC60F41-D21B-4D45-843D-3AF54177B537Q30433083-D6D98DEE-0F2D-42B5-AEB1-A7279A17C0FDQ30603468-0891AA5D-B3C5-4CE2-B609-062A57DE681CQ33432679-D1A8B535-D611-4587-A82B-E658218BE799Q34741989-C3B55FF5-D0C2-454C-BADE-3D606A158873Q35077562-76B61F3D-A96E-4DAF-AF9B-265E1208EB2AQ35192778-3DD38C5F-BD0E-4117-A471-8CB056501371Q36099153-F44201F0-1074-4330-8E0F-26207F1CE8FAQ36155008-E2305D6E-B950-497F-9091-120DF7F2E8D5Q36673366-E8F9B006-31EA-479C-9B40-752F1774B02DQ37102865-B3F679C2-D686-4C58-A2DB-3205A51ECBB9Q37252761-C24CE94E-D0EE-463F-984F-EF75D9D9CD3FQ37452085-E0AB7830-3A87-4562-8296-B32CD39C226DQ38609891-E27F8C81-1B51-4F04-AB7E-196A6F6B154FQ38910076-AD9C9524-9F41-4F3B-ADA5-D4AF65CBA16DQ38994872-A75961C1-01B2-4607-910C-506869A36E30Q39020466-B472462D-38F4-45BF-945C-FBF1367332BBQ39178032-D3B74564-C5A7-4526-9905-D7B5447A5399Q39194791-B3379868-FA10-46BA-B5D3-A628F2ED2B66Q39257189-87B429FE-2436-492F-8623-78F3EEC28C2FQ39375624-D82748BA-F7A6-418E-83E8-C92DACE4FA41Q39695155-0FB92174-30A6-4152-A856-D2AACA9B713BQ39766055-E96FD56B-0543-4823-8D42-B89A0898106BQ39819252-AD2B3C04-898C-453B-BDB5-1372F13F2D17Q40069602-AF486CB0-B00D-454D-B117-DE4697184DD5Q40090326-949088DC-649B-40AE-9812-C176D5ACA6B7Q40192240-71C57763-B735-4C48-BC19-72691C77CF82Q40271389-B93CFB1D-A3F3-453C-8760-612DDB24FC84Q40649067-84875228-3F1D-4F91-9A9E-9E5CE7BF3CD4Q42106686-7D06C4EA-C3B4-402B-8611-AFB802A42CD4Q42176889-49E393A8-9425-471E-B083-F26284A4154BQ52330597-20B565EB-96AB-41ED-8763-CE0C4EF65ABA
P2860
Identification of an essential domain in the herpesvirus VP1/2 tegument protein: the carboxy terminus directs incorporation into capsid assemblons
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Identification of an essential ...... oration into capsid assemblons
@ast
Identification of an essential ...... oration into capsid assemblons
@en
type
label
Identification of an essential ...... oration into capsid assemblons
@ast
Identification of an essential ...... oration into capsid assemblons
@en
prefLabel
Identification of an essential ...... oration into capsid assemblons
@ast
Identification of an essential ...... oration into capsid assemblons
@en
P2860
P356
P1433
P1476
Identification of an essential ...... oration into capsid assemblons
@en
P2093
Gregory Allan Smith
Joy I-Hsuan Lee
P2860
P304
12086-12094
P356
10.1128/JVI.01184-06
P577
2006-09-27T00:00:00Z