Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2
about
Role of dynamin and clathrin in the cellular trafficking of flotillinsFlotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cellsFlotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sortingA bacterial toxin and a nonenveloped virus hijack ER-to-cytosol membrane translocation pathways to cause diseaseIdentification of host cell factors required for intoxication through use of modified cholera toxinClathrin-independent pathways of endocytosis.Toxin instability and its role in toxin translocation from the endoplasmic reticulum to the cytosol.Clathrin-independent pathways do not contribute significantly to endocytic fluxADP-ribosylation factor 6 acts as an allosteric activator for the folded but not disordered cholera toxin A1 polypeptide.Co- and post-translocation roles for HSP90 in cholera Intoxication.Establishment of an in vitro transport assay that reveals mechanistic differences in cytosolic events controlling cholera toxin and T-cell receptor α retro-translocationProtein-disulfide isomerase displaces the cholera toxin A1 subunit from the holotoxin without unfolding the A1 subunitMicrotubule motors power plasma membrane tubulation in clathrin-independent endocytosisDHHC5 protein palmitoylates flotillin-2 and is rapidly degraded on induction of neuronal differentiation in cultured cells.Structural and functional interactions between the cholera toxin A1 subunit and ERdj3/HEDJ, a chaperone of the endoplasmic reticulum.A New Membrane Lipid Raft Gene SpFLT-1 Facilitating the Endocytosis of Vibrio alginolyticus in the Crab Scylla paramamosain.The nucleotide exchange factors Grp170 and Sil1 induce cholera toxin release from BiP to enable retrotranslocation.A Conformational Shift in the Dissociated Cholera Toxin A1 Subunit Prevents Reassembly of the Cholera Holotoxin.The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NADLipid rafts alter the stability and activity of the cholera toxin A1 subunit.Lipid sorting by ceramide structure from plasma membrane to ER for the cholera toxin receptor ganglioside GM1.A single native ganglioside GM1-binding site is sufficient for cholera toxin to bind to cells and complete the intoxication pathway.Expression of flotillins in the human placenta: potential implications for placental transcytosis.The ERdj5-Sel1L complex facilitates cholera toxin retrotranslocationZebrafish Sensitivity to Botulinum NeurotoxinsGanglioside GM1-mediated transcytosis of cholera toxin bypasses the retrograde pathway and depends on the structure of the ceramide domain.RETRACTED: The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signalingMouse Mammary Tumor Virus Signal Peptide Uses a Novel p97-Dependent and Derlin-Independent Retrotranslocation Mechanism To Escape Proteasomal Degradation.Ricin trafficking in plant and mammalian cells.The role of endocytosis in activating and regulating signal transduction.Insights on the trafficking and retro-translocation of glycosphingolipid-binding bacterial toxins.Retrograde transport of protein toxins through the Golgi apparatus.Endocytic trafficking of membrane-bound cargo: a flotillin point of view.Regulation of exosome release by glycosphingolipids and flotillins.Flotillin-1 mediates PrPc endocytosis in the cultured cells during Cu²⁺ stimulation through molecular interaction.Flotillins as regulators of ErbB2 levels in breast cancer.Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo.Roles of flotillins in tumors.Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels.
P2860
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P2860
Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Intoxication of zebrafish and ...... roteins but not Derlin-1 or -2
@ast
Intoxication of zebrafish and ...... roteins but not Derlin-1 or -2
@en
type
label
Intoxication of zebrafish and ...... roteins but not Derlin-1 or -2
@ast
Intoxication of zebrafish and ...... roteins but not Derlin-1 or -2
@en
prefLabel
Intoxication of zebrafish and ...... roteins but not Derlin-1 or -2
@ast
Intoxication of zebrafish and ...... roteins but not Derlin-1 or -2
@en
P2093
P2860
P921
P356
P1476
Intoxication of zebrafish and ...... roteins but not Derlin-1 or -2
@en
P2093
Daniel J-F Chinnapen
David E Saslowsky
Heidi E De Luca
Himani Chinnapen
Jessica S Wagner
Jin Ah Cho
Ramiro H Massol
P2860
P304
P356
10.1172/JCI42958
P407
P577
2010-12-01T00:00:00Z