Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model. - Wikidata - wikimedia - TriplyDB

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

http://www.wikidata.org/entity/Q30479181

about

P1343

Golgi protein GOLM1 is a tissue and urine biomarker of prostate cancer The many faces of neuroendocrine differentiation in prostate cancer progression Role of the TMPRSS2-ERG gene fusion in prostate cancer TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model Neoplasia: the second decade.TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-β signaling.TMPRSS2:ERG gene fusion variants induce TGF-β signaling and epithelial to mesenchymal transition in human prostate cancer cells 1{alpha},25-Dihydroxyvitamin D3 inhibits growth of VCaP prostate cancer cells despite inducing the growth-promoting TMPRSS2:ERG gene fusion.Optical coding of fusion genes using multicolor quantum dots for prostate cancer diagnosis.Antibody-based detection of ERG rearrangement-positive prostate cancer Molecular pathways: targeting ETS gene fusions in cancer.Organoid cultures derived from patients with advanced prostate cancer.Genome Fusion Detection: a novel method to detect fusion genes from SNP-array data.5' UTR control of native ERG and of Tmprss2:ERG variants activity in prostate cancer Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer.Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity In vitro and in vivo model systems used in prostate cancer research.Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challenges.Fusion transcript loci share many genomic features with non-fusion loci.Dual roles of PARP-1 promote cancer growth and progression.Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies.Molecular pathogenesis and progression of prostate cancer The discovery and application of gene fusions in prostate cancer.Distinct genomic aberrations associated with ERG rearranged prostate cancer Recurrent gene fusions in prostate cancer Translocations in epithelial cancers.Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma.The War on Cancer rages on.GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells.TMPRSS2-ERG Fusion Gene Expression in Prostate Tumor Cells and Its Clinical and Biological Significance in Prostate Cancer Progression ERG expression in prostate cancer: biological relevance and clinical implication.FOXA2 is a sensitive and specific marker for small cell neuroendocrine carcinoma of the prostate.Micro-RNA-204 Participates in TMPRSS2/ERG Regulation and Androgen Receptor Reprogramming in Prostate Cancer.Oncogenic mechanisms of HOXB13 missense mutations in prostate carcinogenesis.Sigma1 Targeting to Suppress Aberrant Androgen Receptor Signaling in Prostate Cancer.TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation.Inhibition of BET bromodomain proteins as a therapeutic approach in prostate cancer.Gene fusions by chromothripsis of chromosome 5q in the VCaP prostate cancer cell line.Targeting IGF-IR with ganitumab inhibits tumorigenesis and increases durability of response to androgen-deprivation therapy in VCaP prostate cancer xenografts.PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy.

P2860

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P1343

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P2860

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

http://www.wikidata.org/entity/Q30479181

description

2007 nî lūn-bûn

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Arul M Chinnaiyan

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Bharathi Laxman

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Charles Lee

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Joëlle Tchinda

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Kirsten D Mertz

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Rameen Beroukhim

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Robert L Vessella

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Scott Tomlins

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Sunita R Setlur

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Sven Perner

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P2860

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

Detection of large-scale variation in the human genome

dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data.

Prostate-localized and androgen-regulated expression of the membrane-bound serine protease TMPRSS2.

VCaP, a cell-based model system of human prostate cancer.

Molecular characterization of human prostate carcinoma cell lines.

TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer.

Expression of variant TMPRSS2/ERG fusion messenger RNAs is associated with aggressive prostate cancer.

P304

200-206

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scholarly article

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10.1593/NEO.07103

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3

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P478

9

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P50

Francesca Demichelis

Saravana M Dhanasekaran

P577

2007-03-01T00:00:00Z

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245894386

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17401460

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1838578

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