Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content - Wikidata - wikimedia - TriplyDB

Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content

Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content

http://www.wikidata.org/entity/Q30479724

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Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression SIBLINGs and SPARC families: their emerging roles in pancreatic cancer Molecular mechanisms and clinical applications of angiogenesis Vascular normalization as a therapeutic strategy for malignant and nonmalignant disease.Normalization of the vasculature for treatment of cancer and other diseases.Netrin-4 promotes mural cell adhesion and recruitment to endothelial cells.Hedgehog promotes neovascularization in pancreatic cancers by regulating Ang-1 and IGF-1 expression in bone-marrow derived pro-angiogenic cells.Expression and prognostic value of circulating angiogenic cytokines in pancreatic cancer.SDF-1α induces PDGF-B expression and the differentiation of bone marrow cells into pericytes Elevated PDGFRB gene copy number gain is prognostic for improved survival outcomes in resected malignant pleural mesothelioma Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders.Targeting the PDGF signaling pathway in tumor treatment Endosialin Expression in Metastatic Melanoma Tumor Microenvironment Vasculature: Potential Therapeutic Implications.Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates.Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer.Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models.A novel multiplexed immunoassay identifies CEA, IL-8 and prolactin as prospective markers for Dukes' stages A-D colorectal cancers.HIV Tat 101-mediated loss of pericytes at the blood-brain barrier involves PDGF-BB Mammary tumors that become independent of the type I insulin-like growth factor receptor express elevated levels of platelet-derived growth factor receptors.Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression.Role of bone marrow-derived cells in angiogenesis: focus on macrophages and pericytes.Activation of PDGFr-β Signaling Pathway after Imatinib and Radioimmunotherapy Treatment in Experimental Pancreatic Cancer.Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo.Pericyte-fibroblast transition promotes tumor growth and metastasis.In vitro self-assembly of human pericyte-supported endothelial microvessels in three-dimensional coculture: a simple model for interrogating endothelial-pericyte interactions.Telomeric repeat-binding factor 2: a marker for survival and anti-EGFR efficacy in oral carcinoma Growth factors in tumor microenvironment.Abnormal tumor vasculatures and bone marrow-derived pro-angiogenic cells in cancer.Novel targets for VEGF-independent anti-angiogenic drugs.Recruitment and retention: factors that affect pericyte migration.Heparan sulfate in angiogenesis: a target for therapy.Pericytes: a double-edged sword in cancer therapy.Investigational therapies up to Phase II which target PDGF receptors: potential anti-cancer therapeutics.Angiogenesis in cancer: Anti-VEGF escape mechanisms New therapeutic directions for advanced pancreatic cancer: cell cycle inhibitors, stromal modifiers and conjugated therapies.PDGFRA mRNA is overexpressed in oral cancer patients as compared to normal subjects with a significant trend of overexpression among tobacco users.Pathogenetic significance and possibility as a therapeutic target of platelet derived growth factor.Perivascular PDGFR-β is an independent marker for prognosis in renal cell carcinoma.The Role of PDGFs and PDGFRs in Colorectal Cancer.Tumor angiogenesis and vascular normalization: alternative therapeutic targets.

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Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content

http://www.wikidata.org/entity/Q30479724

description

2007 nî lūn-bûn

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2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Overexpression of PDGF-BB decr ...... reasing tumor pericyte content

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Overexpression of PDGF-BB decr ...... reasing tumor pericyte content

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type

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Overexpression of PDGF-BB decr ...... reasing tumor pericyte content

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Overexpression of PDGF-BB decr ...... reasing tumor pericyte content

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Overexpression of PDGF-BB decr ...... reasing tumor pericyte content

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Overexpression of PDGF-BB decr ...... reasing tumor pericyte content

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Journal of Clinical Investigation

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Overexpression of PDGF-BB decr ...... reasing tumor pericyte content

@en

P2093

Corazon Bucana

http://www.w3.org/2001/XMLSchema#string

Fan Fan

http://www.w3.org/2001/XMLSchema#string

Jane Wey

http://www.w3.org/2001/XMLSchema#string

Lee M Ellis

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Marya F McCarty

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Oliver Stoeltzing

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Ray J Somcio

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Wenbiao Liu

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P2860

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

Roles of nitric oxide synthase inhibition and vascular endothelial growth factor receptor-2 inhibition on vascular morphology and function in an in vivo model of pancreatic cancer.

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes.

Diversity within pericytes.

Pericytes and the pathogenesis of diabetic retinopathy.

Endothelial-pericyte interactions in angiogenesis.

Pericytes: cell biology and pathology.

Developmental roles of platelet-derived growth factors.

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2114-2122

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10.1172/JCI31334

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8

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117

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17641778

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1913488

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