Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner. - Wikidata - wikimedia - TriplyDB

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

http://www.wikidata.org/entity/Q30480507

about

F-actin clustering and cell dysmotility induced by the pathological W148R missense mutation of filamin B at the actin-binding domain Filamin structure, function and mechanics: are altered filamin-mediated force responses associated with human disease?Filamins in mechanosensing and signaling.Quantitative trait loci, genes, and polymorphisms that regulate bone mineral density in mouse Formin 1 and filamin B physically interact to coordinate chondrocyte proliferation and differentiation in the growth plate Disease-associated mutations in the actin-binding domain of filamin B cause cytoplasmic focal accumulations correlating with disease severity.Targeting filamin B induces tumor growth and metastasis via enhanced activity of matrix metalloproteinase-9 and secretion of VEGF-A.Actin microfilament mediates osteoblast Cbfa1 responsiveness to BMP2 under simulated microgravity Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain Age-dependent alteration of TGF-β signalling in osteoarthritis.TGFβ and BMP Dependent Cell Fate Changes Due to Loss of Filamin B Produces Disc Degeneration and Progressive Vertebral Fusions.Phenotype and genotype in patients with Larsen syndrome: clinical homogeneity and allelic heterogeneity in seven patients ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3.Characteristic calcaneal ossification: an additional early radiographic finding in infants with fibrodysplasia ossificans progressiva.Filamin B Loss-of-Function Mutation in Dimerization Domain Causes Autosomal-Recessive Spondylocarpotarsal Synostosis Syndrome with Rib Anomalies.Comparative analysis of the two extremes of FLNB-mutated autosomal dominant disease spectrum: from clinical phenotypes to cellular and molecular findings.

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P2860

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

http://www.wikidata.org/entity/Q30480507

description

2007 nî lūn-bûn

@nan

2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

@ast

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

@en

type

label

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

@ast

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

@en

prefLabel

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

@ast

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

@en

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Journal of Cell Biology

P1476

Filamin B represses chondrocyte hypertrophy in a Runx2/Smad3-dependent manner.

@en

P2093

Gerard Karsenty

http://www.w3.org/2001/XMLSchema#string

Hwa-Jin Baek

http://www.w3.org/2001/XMLSchema#string

Lihua Zheng

http://www.w3.org/2001/XMLSchema#string

Monica J Justice

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in FLNB cause boomerang dysplasia

Structural and functional aspects of filamins

Filamins as integrators of cell mechanics and signalling

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

Repression of Runx2 function by TGF-beta through recruitment of class II histone deacetylases by Smad3.

A twist code determines the onset of osteoblast differentiation

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

Localized mutations in the gene encoding the cytoskeletal protein filamin A cause diverse malformations in humans.

Reaching a genetic and molecular understanding of skeletal development.

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121-128

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scholarly article

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10.1083/JCB.200703113

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1

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178

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2007-07-01T00:00:00Z

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6230622

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17606870

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2064428

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