The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors. - Wikidata - wikimedia - TriplyDB

The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors.

The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors.

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The expanding role of immunopharmacology: IUPHAR Review 16 The effects of microRNA on the absorption, distribution, metabolism and excretion of drugs Vascular targets for cannabinoids: animal and human studies Something old, something new and something very old: drugs for treating type 2 diabetes Are cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review Extending the translational potential of targeting NO/cGMP-regulated pathways in the CVS Constrictor prostanoids and uridine adenosine tetraphosphate: vascular mediators and therapeutic targets in hypertension and diabetes Synthetic androgens as designer supplements The orphan receptor NOR1 participates in isoprenaline-induced cardiac hypertrophy by regulating PARP-1 Stress-induced pain: a target for the development of novel therapeutics Sex differences in animal models of psychiatric disorders.The dual PPARα/γ agonist aleglitazar increases the number and function of endothelial progenitor cells: implications for vascular function and atherogenesis.The fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies.Of mice and men: modelling post-stroke depression experimentally.Therapeutic interventions in sepsis: current and anticipated pharmacological agents Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?Differences in the rate of oestrogen-induced apoptosis in breast cancer by oestradiol and the triphenylethylene bisphenol.Synthetic gestagens exert differential effects on arterial thrombosis and aortic gene expression in ovariectomized apolipoprotein E-deficient mice Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent.YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells.Simulation with cells in vitro of tamoxifen treatment in premenopausal breast cancer patients with different CYP2D6 genotypes.Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma.Differential activation of human constitutive androstane receptor and its SV23 and SV24 splice variants by rilpivirine and etravirine Clinically used selective oestrogen receptor modulators increase LDL receptor activity in primary human lymphocytes.Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm?Cardiac NO signalling in the metabolic syndrome.Crucial role of androgen receptor in vascular H2S biosynthesis induced by testosterone.Δ(9) Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells.Haloperidol inhibits the development of atherosclerotic lesions in LDL receptor knockout mice Therapeutic perspectives of epigenetically active nutrients.Kaempferol enhances endothelium-dependent relaxation in the porcine coronary artery through activation of large-conductance Ca(2+) -activated K(+) channels Peroxisomes in Different Skeletal Cell Types during Intramembranous and Endochondral Ossification and Their Regulation during Osteoblast Differentiation by Distinct Peroxisome Proliferator-Activated Receptors.A Sativex(®) -like combination of phytocannabinoids as a disease-modifying therapy in a viral model of multiple sclerosis.PKPD modelling to predict altered disposition of 1α,25-dihydroxyvitamin D3 in mice due to dose-dependent regulation of CYP27B1 on synthesis and CYP24A1 on degradation.Acute morphine affects the rat circadian clock via rhythms of phosphorylated ERK1/2 and GSK3β kinases and Per1 expression in the rat suprachiasmatic nucleus Activation of PPAR-δ induces microRNA-100 and decreases the uptake of very low-density lipoprotein in endothelial cells.Identification of matrine as a promising novel drug for hepatic steatosis and glucose intolerance with HSP72 as an upstream target Biased β2-adrenoceptor signalling in heart failure: pathophysiology and drug discovery.Aldosterone down-regulates the slowly activated delayed rectifier potassium current in adult guinea pig cardiomyocytes Cryptotanshinone, an orally bioactive herbal compound from Danshen, attenuates atherosclerosis in apolipoprotein E-deficient mice: role of lectin-like oxidized LDL receptor-1 (LOX-1).

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The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors.

http://www.wikidata.org/entity/Q30486738

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2013 nî lūn-bûn

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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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British Journal of Pharmacology

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The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors.

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Anthony J Harmar

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CGTP Collaborators

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Helen E Benson

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John A Peters

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Identification of an endogenous ligand bound to a native orphan nuclear receptor

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

Identification of a nuclear receptor for bile acids

Bile acids: natural ligands for an orphan nuclear receptor

Rev-erbalpha, a heme sensor that coordinates metabolic and circadian pathways

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes

Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor.

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1652-1675

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10.1111/BPH.12448

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8

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170

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Michael Spedding

Steve Alexander

Joanna L. Sharman

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2013-12-01T00:00:00Z

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261532724

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24528240

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3892290

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