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The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.

The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.

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Use of bone morphogenetic proteins in mesenchymal stem cell stimulation of cartilage and bone repair The expanding role of immunopharmacology: IUPHAR Review 16 Ten things you should know about protein kinases: IUPHAR Review 14 Immunosuppressive and anti-inflammatory properties of engineered nanomaterials Postconditioning signalling in the heart: mechanisms and translatability Constrictor prostanoids and uridine adenosine tetraphosphate: vascular mediators and therapeutic targets in hypertension and diabetes Therapeutic targets of triple-negative breast cancer: a review The role of cannabinoids in adult neurogenesis Dopamine receptors - IUPHAR Review 13 Amyloid β: one of three danger-associated molecules that are secondary inducers of the proinflammatory cytokines that mediate Alzheimer's disease Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders Proteinases, their receptors and inflammatory signalling: the Oxford South Parks Road connection TRP channels in the skin.The CO donor CORM-2 inhibits LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts.ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21((CIP1/WAF1)) in human cancer cells.JAK2/STAT5/Bcl-xL signalling is essential for erythropoietin-mediated protection against apoptosis induced in PC12 cells by the amyloid β-peptide Aβ25-35.Novel therapeutic targets in myeloma bone disease.The tyrosine kinase inhibitor bafetinib inhibits PAR2-induced activation of TRPV4 channels in vitro and pain in vivo IL-6 in diabetes and cardiovascular complications.Bone morphogenetic proteins and their antagonists: current and emerging clinical uses.Pharmacological regulators of autophagy and their link with modulators of lupus disease Purinergic neuromuscular transmission in the gastrointestinal tract; functional basis for future clinical and pharmacological studies Therapeutic interventions in sepsis: current and anticipated pharmacological agents Rare platelet GPCR variants: what can we learn?Potent anti-inflammatory effects of the narrow spectrum kinase inhibitor RV1088 on rheumatoid arthritis synovial membrane cells.Prostaglandin E2 and the EP receptors in malignancy: possible therapeutic targets?Luteolin is effective in the non-small cell lung cancer model with L858R/T790M EGF receptor mutation and erlotinib resistance.YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice Treatment with LPS plus INF-γ induces the expression and function of muscarinic acetylcholine receptors, modulating NIH3T3 cell proliferation: participation of NOS and COX.Identification of novel insulin mimetic drugs by quantitative total internal reflection fluorescence (TIRF) microscopy.Preclinical development of AMG 139, a human antibody specifically targeting IL-23 YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells.IL-1β and IL-18: inflammatory markers or mediators of hypertension?Molecular targets of the multifunctional iron-chelating drug, M30, in the brains of mouse models of type 2 diabetes mellitus PPemd26, an anthraquinone derivative, suppresses angiogenesis via inhibiting VEGFR2 signalling.Neuroprotective effects of the anti-cancer drug sunitinib in models of HIV neurotoxicity suggests potential for the treatment of neurodegenerative disorders.A non-erythropoietic peptide derivative of erythropoietin decreases susceptibility to diet-induced insulin resistance in mice.κ Opioid receptor ligands regulate angiogenesis in development and in tumours.Effect of naltrexone on neuropathic pain in mice locally transfected with the mutant μ-opioid receptor gene in spinal cord.

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The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.

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2013 nî lūn-bûn

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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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British Journal of Pharmacology

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The Concise Guide to PHARMACOLOGY 2013/14: catalytic receptors.

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Anthony J Harmar

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CGTP Collaborators

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Helen E Benson

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John A Peters

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Galectin-1, a natural ligand for the receptor-type protein tyrosine phosphatase CD45

Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

Role of AMP-activated protein kinase in mechanism of metformin action

Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors

A Toll-like receptor recognizes bacterial DNA

Discrimination of bacterial lipoproteins by Toll-like receptor 6

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

The inflammasomes

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10.1111/BPH.12449

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8

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170

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Michael Spedding

Steve Alexander

Joanna L. Sharman

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2013-12-01T00:00:00Z

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262046627

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24528241

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