A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain - Wikidata - wikimedia - TriplyDB

A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain

A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain

http://www.wikidata.org/entity/Q30487486

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Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells Genome-wide association study identified CNP12587 region underlying height variation in Chinese females Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases.Down-regulation of Nedd4L is associated with the aggressive progression and worse prognosis of malignant glioma.The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly.

P2860

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P2860

A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain

http://www.wikidata.org/entity/Q30487486

description

2009 nî lūn-bûn

@nan

2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

A human polymorphism affects N ...... at contain or lack a C2 domain

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A human polymorphism affects N ...... at contain or lack a C2 domain

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type

label

A human polymorphism affects N ...... at contain or lack a C2 domain

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A human polymorphism affects N ...... at contain or lack a C2 domain

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prefLabel

A human polymorphism affects N ...... at contain or lack a C2 domain

@ast

A human polymorphism affects N ...... at contain or lack a C2 domain

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1471-2121-10-26

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BMC Cell Biology

P1476

A human polymorphism affects N ...... at contain or lack a C2 domain

@en

P2093

Andreas Rohrwasser

http://www.w3.org/2001/XMLSchema#string

Bonnie L Blazer-Yost

http://www.w3.org/2001/XMLSchema#string

Nicholas F Garrone

http://www.w3.org/2001/XMLSchema#string

Robert B Weiss

http://www.w3.org/2001/XMLSchema#string

P2860

U box proteins as a new family of ubiquitin-protein ligases

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

A novel splice-site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families

A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

Liddle disease caused by a missense mutation of beta subunit of the epithelial sodium channel gene

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome

A de novo missense mutation of the beta subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity

P2888

1471-2121-10-26

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26

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scholarly article

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10.1186/1471-2121-10-26

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10

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Jean-Marc Lalouel

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2009-04-13T00:00:00Z

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24275666

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1043617741

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19364400

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2678989

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