The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
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The Warburg effect and drug resistanceExtracellular nicotinamide phosphoribosyltransferase, a new cancer metabokineExercise effects on perivascular adipose tissue: endocrine and paracrine determinants of vascular function.Pharmacogenomics of off-target adverse drug reactions.Glucagon-like peptide-1 receptor signalling reduces microvascular thrombosis, nitro-oxidative stress and platelet activation in endotoxaemic mice.First-in-human randomized study of bimekizumab, a humanized monoclonal antibody and selective dual inhibitor of IL-17A and IL-17F, in mild psoriasisOzanimod (RPC1063) is a potent sphingosine-1-phosphate receptor-1 (S1P1 ) and receptor-5 (S1P5 ) agonist with autoimmune disease-modifying activity.NVP-TAE684 reverses multidrug resistance (MDR) in human osteosarcoma by inhibiting P-glycoprotein (PGP1) function.The role of apolipoprotein N-acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target.Vitamin D receptor agonists regulate ocular developmental angiogenesis and modulate expression of dre-miR-21 and VEGF.Monoclonal antibodies: the new magic bullets for allergy: IUPHAR Review 17.Pharmacological characterization of the opioid inactive isomers (+)-naltrexone and (+)-naloxone as antagonists of toll-like receptor 4Immunotherapy of cancer: from monoclonal to oligoclonal cocktails of anti-cancer antibodies: IUPHAR Review 18.Berberine improves mesenteric artery insulin sensitivity through up-regulating insulin receptor-mediated signalling in diabetic ratsPreventive and chronic mineralocorticoid receptor antagonism is highly beneficial in obese SHHF rats.Novel application assigned to toluquinol: inhibition of lymphangiogenesis by interfering with VEGF-C/VEGFR-3 signalling pathway.A novel protein tyrosine phosphatase 1B inhibitor with therapeutic potential for insulin resistanceAntagonizing midkine accelerates fracture healing in mice by enhanced bone formation in the fracture callusMitogen-inducible gene-6 partly mediates the inhibitory effects of prenatal dexamethasone exposure on endochondral ossification in long bones of fetal rats.Identification of A3 adenosine receptor agonists as novel non-narcotic analgesics.Clinical trials for authorized biosimilars in the European Union: a systematic review.Physiologically relevant binding affinity quantification of monoclonal antibody PF-00547659 to mucosal addressin cell adhesion molecule for in vitro in vivo correlationα1B -Adrenoceptor signalling regulates bone formation through the up-regulation of CCAAT/enhancer-binding protein δ expression in osteoblasts.Decursin enhances TRAIL-induced apoptosis through oxidative stress mediated- endoplasmic reticulum stress signalling in non-small cell lung cancersCompound 9a, a novel synthetic histone deacetylase inhibitor, protects against septic injury in mice by suppressing MAPK signalling.Endothelin-1 suppresses insulin-stimulated Akt phosphorylation and glucose uptake via GPCR kinase 2 in skeletal muscle cells.Madecassoside ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting the generation of hepatocyte growth factor via PPAR-γ in colon.Key role of heat shock protein 90 in leptin-induced STAT3 activation and feeding regulation.The Dickkopf1-cytoskeleton-associated protein 4 axis creates a novel signalling pathway and may represent a molecular target for cancer therapy.Changes in the plasma membrane in metabolic disease: impact of the membrane environment on G protein-coupled receptor structure and function.NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease.Protein S-sulfhydration by hydrogen sulfide in cardiovascular system.Microglia antioxidant systems and redox signalling.ROS in gastrointestinal inflammation: Rescue Or Sabotage?Translating advances in the molecular basis of schizophrenia into novel cognitive treatment strategies.Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization.Influence of opioids on immune function in patients with cancer pain: from bench to bedside.Current and future therapies for addressing the effects of inflammation on HDL cholesterol metabolism.Immunology proves a great success for treating systemic autoimmune diseases - a perspective on immunopharmacology: IUPHAR Review 23.Utilizing melatonin to combat bacterial infections and septic injury.
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The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
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2015 nî lūn-bûn
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2015 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2015 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
@ast
The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
@en
type
label
The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
@ast
The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
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prefLabel
The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
@ast
The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
@en
P2093
P50
P356
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The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors.
@en
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CGTP Collaborators
Doriano Fabbro
Eamonn Kelly
Helen E Benson
John A Peters
Neil Marrion
P304
P356
10.1111/BPH.13353
P407
P577
2015-12-01T00:00:00Z