Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases. - Wikidata - wikimedia - TriplyDB

Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.

Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.

http://www.wikidata.org/entity/Q30488818

about

Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cells Cortactin phosphorylated by ERK1/2 localizes to sites of dynamic actin regulation and is required for carcinoma lamellipodia persistence Cortactin as a target for FAK in the regulation of focal adhesion dynamics Microtubules as platforms for assaying actin polymerization in vivo Polarized endocytosis of the keratinocyte growth factor receptor in migrating cells: role of SRC-signaling and cortactin pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1)A nucleator arms race: cellular control of actin assembly Tyrosine phosphorylation of cortactin by the FAK-Src complex at focal adhesions regulates cell motility The homolog of the five SH3-domain protein (HOFI/SH3PXD2B) regulates lamellipodia formation and cell spreading Cortactin controls cell motility and lamellipodial dynamics by regulating ECM secretion Immunoinhibitory adapter protein Src homology domain 3 lymphocyte protein 2 (SLy2) regulates actin dynamics and B cell spreading.Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility.Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin.Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation.Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.Quantitative kinetic study of the actin-bundling protein L-plastin and of its impact on actin turn-over.Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.Cortactin is implicated in murine zygotic development.Hax-1 is required for Rac1-Cortactin interaction and ovarian carcinoma cell migration.Cortactin modulates RhoA activation and expression of Cip/Kip cyclin-dependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells.RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes Inversin/Nephrocystin-2 is required for fibroblast polarity and directional cell migration.Cortactin: a multifunctional regulator of cellular invasiveness HDAC6 deacetylase activity is critical for lipopolysaccharide-induced activation of macrophages Extracellular signal-regulated kinase (ERK) regulates cortactin ubiquitination and degradation in lung epithelial cells The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility.Novel role of cortactin in G protein-coupled receptor agonist-induced nuclear export and degradation of p21Cip1.The S40 residue in HIV-1 Gag p6 impacts local and distal budding determinants, revealing additional late domain activities.The actin binding proteins cortactin and HS1 are dispensable for platelet actin nodule and megakaryocyte podosome formation.Cortactin in cell migration and cancer at a glance The non-canonical roles of clathrin and actin in pathogen internalization, egress and spread.Steering cell migration: lamellipodium dynamics and the regulation of directional persistence.Role of cellular cytoskeleton in epithelial-mesenchymal transition process during cancer progression.The Arp2/3 inhibitory protein arpin induces cell turning by pausing cell migration.The protein tyrosine phosphatase DEP-1/PTPRJ promotes breast cancer cell invasion and metastasis.The actin regulatory protein HS1 is required for antigen uptake and presentation by dendritic cells.Cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe DSS-induced colitis.How distinct Arp2/3 complex variants regulate actin filament assembly.

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Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases.

http://www.wikidata.org/entity/Q30488818

description

2009 nî lūn-bûn

@nan

2009 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Cortactin promotes migration a ...... n by signaling to Rho-GTPases.

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Cortactin promotes migration a ...... n by signaling to Rho-GTPases.

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type

label

Cortactin promotes migration a ...... n by signaling to Rho-GTPases.

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Cortactin promotes migration a ...... n by signaling to Rho-GTPases.

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Cortactin promotes migration a ...... n by signaling to Rho-GTPases.

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Cortactin promotes migration a ...... n by signaling to Rho-GTPases.

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MBC.E08-12-1180

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Molecular Biology of the Cell

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Cortactin promotes migration a ...... on by signaling to Rho-GTPases

@en

P2093

Frank P L Lai

http://www.w3.org/2001/XMLSchema#string

J Margit Oelkers

http://www.w3.org/2001/XMLSchema#string

J Victor Small

http://www.w3.org/2001/XMLSchema#string

Jan Faix

http://www.w3.org/2001/XMLSchema#string

Malgorzata Szczodrak

http://www.w3.org/2001/XMLSchema#string

Markus Ladwein

http://www.w3.org/2001/XMLSchema#string

Simona Polo

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Sonja Auinger

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Stefanie Benesch

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P2860

Localized Rac activation dynamics visualized in living cells

Erk/Src phosphorylation of cortactin acts as a switch on-switch off mechanism that controls its ability to activate N-WASP

A Hip1R-cortactin complex negatively regulates actin assembly associated with endocytosis

Human subtelomeric WASH genes encode a new subclass of the WASP family

Coronin 1B antagonizes cortactin and remodels Arp2/3-containing actin branches in lamellipodia.

WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport

p53-cofactor JMY is a multifunctional actin nucleation factor

Identification of a novel cortactin SH3 domain-binding protein and its localization to growth cones of cultured neurons

Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.

RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery.

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3209-3223

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scholarly article

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10.1091/MBC.E08-12-1180

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14

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P478

20

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Klemens Rottner

Filippo Acconcia

Theresia Stradal

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2009-05-20T00:00:00Z

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19458196

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2710823

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