Axonal targeting of Trk receptors via transcytosis regulates sensitivity to neurotrophin responses
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Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling.Mitotic motors coregulate microtubule patterns in axons and dendritesRegulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon RegenerationPrecursor and mature NGF live tracking: one versus many at a time in the axons.BDNF regulates Rab11-mediated recycling endosome dynamics to induce dendritic branchingCoronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival.Drive the Car(go)s-New Modalities to Control Cargo Trafficking in Live CellsEmergent Role of Coronin-1a in Neuronal Signaling.The neurotrophin receptor signaling endosome: Where trafficking meets signaling.Harnessing the power of the endosome to regulate neural development.Trk activation of the ERK1/2 kinase pathway stimulates intermediate chain phosphorylation and recruits cytoplasmic dynein to signaling endosomes for retrograde axonal transportMechanisms of polarized membrane trafficking in neurons -- focusing in on endosomes.Endocytosis and endosomes at the crossroads of regulating trafficking of axon outgrowth-modifying receptors.Trafficking guidance receptorsAlterations of EHD1/EHD4 protein levels interfere with L1/NgCAM endocytosis in neurons and disrupt axonal targetingCombining cell-based therapies and neural prostheses to promote neural survivalEndosome-mediated retrograde axonal transport of P2X3 receptor signals in primary sensory neuronsAxonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPaseCalsyntenin-1 regulates axon branching and endosomal trafficking during sensory neuron development in vivo.Three-dimensional distribution of TrkA neurotrophin receptors in neurite varicosities of differentiated PC12 cells treated with NGF determined by immunoelectron tomography.Mechanisms and function of dendritic exocytosis.Isoform-specific dephosphorylation of dynamin1 by calcineurin couples neurotrophin receptor endocytosis to axonal growth.Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons.TBC1D12 is a novel Rab11-binding protein that modulates neurite outgrowth of PC12 cells.RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome.Intracellular LINGO-1 negatively regulates Trk neurotrophin receptor signaling.Membrane Trafficking in Neuronal Development: Ins and Outs of Neural Connectivity.Axon Transport and Neuropathy: Relevant Perspectives on the Etiopathogenesis of Familial Dysautonomia.Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners.Endosomal acidification by Na+/H+ exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling.Rab5 and Rab4 regulate axon elongation in the Xenopus visual system.Endocytic trafficking of neurotrophins in neural development.Endosomal pH in neuronal signaling and synaptic transmission: role of Na(+)/H(+) exchanger NHE5.Pro-neurotrophins, sortilin, and nociception.The role of rab proteins in neuronal cells and in the trafficking of neurotrophin receptors.The sugar code in neuronal physiology.The dendritic SNARE fusion machinery involved in AMPARs insertion during long-term potentiation.Biogenesis and function of the NGF/TrkA signaling endosomeAttractive and repulsive factors act through multi-subunit receptor complexes to regulate nerve fiber growth.Membrane turnover and receptor trafficking in regenerating axons.
P2860
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P2860
Axonal targeting of Trk receptors via transcytosis regulates sensitivity to neurotrophin responses
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Axonal targeting of Trk recept ...... vity to neurotrophin responses
@ast
Axonal targeting of Trk recept ...... vity to neurotrophin responses
@en
type
label
Axonal targeting of Trk recept ...... vity to neurotrophin responses
@ast
Axonal targeting of Trk recept ...... vity to neurotrophin responses
@en
prefLabel
Axonal targeting of Trk recept ...... vity to neurotrophin responses
@ast
Axonal targeting of Trk recept ...... vity to neurotrophin responses
@en
P2093
P2860
P1476
Axonal targeting of Trk recept ...... vity to neurotrophin responses
@en
P2093
Alissa Richmond
Maria Ascaño
Philip Borden
P2860
P304
11674-11685
P356
10.1523/JNEUROSCI.1542-09.2009
P407
P577
2009-09-01T00:00:00Z