Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. - Wikidata - wikimedia - TriplyDB

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

http://www.wikidata.org/entity/Q30492569

about

The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression Identification and differentiation of PDX1 β-cell progenitors within the human pancreatic epithelium Identifying novel transcriptional components controlling energy metabolism The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells Transcription factor regulation of pancreatic organogenesis, differentiation and maturation RFX2 Is a Major Transcriptional Regulator of Spermiogenesis Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3 Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors.Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation.Many faces of monogenic diabetes Regulatory Factor X (RFX)-mediated transcriptional rewiring of ciliary genes in animals.Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish.Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes.Functional specialization of sensory cilia by an RFX transcription factor isoform A gene expression atlas of the domestic pig Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling.Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish.An integrated cell purification and genomics strategy reveals multiple regulators of pancreas development.New insights into endocrine pancreatic development: the role of environmental factors.G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis The Basic Helix-Loop-Helix Transcription Factor NEUROG3 Is Required for Development of the Human Endocrine Pancreas.DICER Inactivation Identifies Pancreatic β-Cell "Disallowed" Genes Targeted by MicroRNAs.Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells.The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation.Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration Organogenesis and functional genomics of the endocrine pancreas Rfx6 maintains the functional identity of adult pancreatic β cells.The combined effect of PDX1, epidermal growth factor and poly-L-ornithine on human amnion epithelial cells' differentiation Deconstructing pancreas developmental biology.Developmental programming of neonatal pancreatic β-cells by a maternal low-protein diet in rats involves a switch from proliferation to differentiation.ChREBP mediates glucose-stimulated pancreatic β-cell proliferation.Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.REST represses a subset of the pancreatic endocrine differentiation program.RFX2 is broadly required for ciliogenesis during vertebrate development.Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions.LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells.Genetic evidence that Nkx2.2 acts primarily downstream of Neurog3 in pancreatic endocrine lineage development MiRNAs in β-Cell Development, Identity, and Disease.

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P2860

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development.

http://www.wikidata.org/entity/Q30492569

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Rfx6 is an Ngn3-dependent wing ...... reatic islet cell development.

@ast

Rfx6 is an Ngn3-dependent wing ...... reatic islet cell development.

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type

label

Rfx6 is an Ngn3-dependent wing ...... reatic islet cell development.

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Rfx6 is an Ngn3-dependent wing ...... reatic islet cell development.

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prefLabel

Rfx6 is an Ngn3-dependent wing ...... reatic islet cell development.

@ast

Rfx6 is an Ngn3-dependent wing ...... reatic islet cell development.

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Rfx6 is an Ngn3-dependent wing ...... reatic islet cell development.

@en

P2093

Anthony Beucher

http://www.w3.org/2001/XMLSchema#string

Bernard Peers

http://www.w3.org/2001/XMLSchema#string

Christophe Orvain

http://www.w3.org/2001/XMLSchema#string

Georg Mellitzer

http://www.w3.org/2001/XMLSchema#string

Josselin Soyer

http://www.w3.org/2001/XMLSchema#string

Julien Vermot

http://www.w3.org/2001/XMLSchema#string

Lydie Flasse

http://www.w3.org/2001/XMLSchema#string

Marianne L Voz

http://www.w3.org/2001/XMLSchema#string

Wolfgang Raffelsberger

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of novel human tissue-specific RFX transcription factors

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

Morphants: a new systematic vertebrate functional genomics approach

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

Function and regulation of zebrafish nkx2.2a during development of pancreatic islet and ducts

Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells

Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

Novel function of the ciliogenic transcription factor RFX3 in development of the endocrine pancreas

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203-212

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scholarly article

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10.1242/DEV.041673

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P433

2

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137

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Gérard Gradwohl

Philippe Ravassard

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2010-01-01T00:00:00Z

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40812254

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20040487

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2799156

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