Null mutation of alpha1D Ca2+ channel gene results in deafness but no vestibular defect in mice - Wikidata - wikimedia - TriplyDB

Null mutation of alpha1D Ca2+ channel gene results in deafness but no vestibular defect in mice

Null mutation of alpha1D Ca2+ channel gene results in deafness but no vestibular defect in mice

http://www.wikidata.org/entity/Q30492652

about

Ion channel gene expression in the inner ear Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells.Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing Differential expression of otoferlin in brain, vestibular system, immature and mature cochlea of the rat Relating structure and function of inner hair cell ribbon synapses.Developmental refinement of hair cell synapses tightens the coupling of Ca2+ influx to exocytosis.Hair cell ribbon synapses.Dominant-negative inhibition of M-like potassium conductances in hair cells of the mouse inner ear Posthearing Ca(2+) currents and their roles in shaping the different modes of firing of spiral ganglion neurons Molecular biology of hearing.Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses.Functional properties of synaptic transmission in primary sense organs Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine.Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1.Developmental alterations in the biophysical properties of Ca(v) 1.3 Ca(2+) channels in mouse inner hair cells.EF-hand protein Ca2+ buffers regulate Ca2+ influx and exocytosis in sensory hair cells Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.Insights into electrosensory organ development, physiology and evolution from a lateral line-enriched transcriptome Rab Interacting Molecules 2 and 3 Directly Interact with the Pore-Forming CaV1.3 Ca2+ Channel Subunit and Promote Its Membrane Expression.Molecular microdomains in a sensory terminal, the vestibular calyx ending Functional features of trans-differentiated hair cells mediated by Atoh1 reveals a primordial mechanism.Quantal and nonquantal transmission in calyx-bearing fibers of the turtle posterior crista.Ribbon synapses in zebrafish hair cells.Conditional deletion of pejvakin in adult outer hair cells causes progressive hearing loss in mice.Levels of Ca(V)1.2 L-Type Ca(2+) Channels Peak in the First Two Weeks in Rat Hippocampus Whereas Ca(V)1.3 Channels Steadily Increase through Development.Molecular identity and functional properties of a novel T-type Ca2+ channel cloned from the sensory epithelia of the mouse inner ear An autism-associated mutation in CaV1.3 channels has opposing effects on voltage- and Ca(2+)-dependent regulation.Presynaptic CaV1.3 channels regulate synaptic ribbon size and are required for synaptic maintenance in sensory hair cells.Innervation regulates synaptic ribbons in lateral line mechanosensory hair cells Precise toxigenic ablation of intermediate cells abolishes the "battery" of the cochlear duct The molecular architecture of ribbon presynaptic terminals AMPA receptor-mediated rapid EPSCs in vestibular calyx afferents.Ca2+-binding protein 2 inhibits Ca2+-channel inactivation in mouse inner hair cells.Calcium-dependent inactivation of calcium channels in cochlear hair cells of the chicken.Single-channel L-type Ca2+ currents in chicken embryo semicircular canal type I and type II hair cells.Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs.The synaptic ribbon is critical for sound encoding at high rates and with temporal precision.Developmental changes in two voltage-dependent sodium currents in utricular hair cells.

P2860

Q24650344-1DD94C2B-36BC-4CFF-9C13-C860C1D1F977 Q27317317-8CEFEF37-BD4D-4ECF-BC71-3649BD0E90DA Q27326298-0C938B6C-599C-4F3C-8B79-7D78FBB9EAF1 Q27347987-E5F3987E-CB36-4C1D-B569-8B77DDA30D33 Q28084651-472CF5B8-508F-42E3-B22C-8590AFA93F3D Q28572458-9F364269-C503-453E-A36E-1E86A8694E8E Q30407369-AA0FFF2A-E508-40F7-A7D5-8F97BE8C5DCC Q30419502-50E09915-BFBC-4300-BFA5-547F51F303BE Q30432571-99B86BD7-65BF-420F-9C4E-D7DDABCEBEDA Q30440196-5F0C9C71-790D-498F-AC3B-431B72CC502A Q30454639-E059B803-4AF8-44A6-9239-0879AEAC30A8 Q30467847-2A3AE638-8EEA-449A-953E-987C78BCA737 Q30479008-991C41E7-FF3D-4BF0-A89F-651E516ACC0E Q30482047-2A468984-89BD-46D9-8CBE-80EA4B7B01D1 Q30484125-0E68B199-4B14-4B61-A7F6-C1F668A2BCEE Q30492373-020FD575-F223-4648-A158-40E94628C1AD Q30541397-0DE51B96-1BAE-4D7E-8B79-63FECB682E55 Q30625597-96FC84B3-94EA-4D87-BA8C-D2FDD494DB63 Q33639546-EFD2BED0-BA0D-4A6A-9A33-C80BD556A612 Q33675636-DFF94B04-3BF2-4227-A077-B89BE8F00C99 Q33774751-771DAE1B-B674-4A6A-9FD3-F6BE73946270 Q35748331-CDA935C0-1C67-4C75-8BE1-07CBB091C2AC Q35860728-71897B19-55B7-4027-9B24-26B3EA034507 Q36096504-86D45804-7166-4F1B-9BB8-6AD0FFF1093D Q36204844-F5CBC905-0DC2-43E4-85E5-5F4A49BC5327 Q36250131-23145284-07D4-42AD-9DD5-FC75BD8A6907 Q36337465-01F56507-2E70-4A1D-B6FB-1FAAEBA95865 Q36956889-D1A2422E-7040-4F99-A347-8DA4CEDC6CE6 Q36964814-35D89CDB-BD29-4CEE-96FF-D4BA54F55BD0 Q37032158-AF3B79EF-D2EB-46E0-98B0-6E8ACE18C394 Q37036405-765C859C-7D36-4330-80CF-1B289C10E992 Q37142101-7A2ED45A-7EB9-450E-8619-1321E8A5DD97 Q37239696-B017211A-7737-4A08-A719-4E7064EFBBC8 Q38905230-62BE3997-BEBE-40CC-B45A-41802FB58EB2 Q42318112-BFCF6A9D-B8C5-4232-B829-5710CF58CF19 Q42627272-C2659DF4-1844-490A-AC3F-25E43A389820 Q42685487-7F9CE2F0-F53F-427A-8BEC-4BDD7A11F4D4 Q46460297-49832BE4-2F70-43F4-BCA2-A331FBEF613B Q47867981-BBCF2D9D-A5D9-4596-BF55-F0C0E0119706 Q48649635-BBD4BDE7-9D20-4F2C-95B8-0E0D9BE622D8

P2860

Null mutation of alpha1D Ca2+ channel gene results in deafness but no vestibular defect in mice

http://www.wikidata.org/entity/Q30492652

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Null mutation of alpha1D Ca2+ ...... t no vestibular defect in mice

@ast

Null mutation of alpha1D Ca2+ ...... t no vestibular defect in mice

@en

type

label

Null mutation of alpha1D Ca2+ ...... t no vestibular defect in mice

@ast

Null mutation of alpha1D Ca2+ ...... t no vestibular defect in mice

@en

prefLabel

Null mutation of alpha1D Ca2+ ...... t no vestibular defect in mice

@ast

Null mutation of alpha1D Ca2+ ...... t no vestibular defect in mice

@en

P1433

Q30492652-33B16E8E-E91F-4D29-8001-FC1C6CD5A90A

P1476

Q30492652-DB680107-49EE-4A71-8A29-A7DCC1141A65

P2093

Q30492652-238B7FF2-588D-4AF8-AC75-F8D2AFDF599D

Q30492652-38F19E4D-D5BB-4940-9916-81D3734AF4C4

Q30492652-49766D0E-7471-4180-9C93-AFBEE37C4149

Q30492652-A1456642-4176-4978-9CC7-073972C94165

Q30492652-C2CF2765-98F8-4541-B0C6-C458C6463F91

Q30492652-E5EAD39B-4565-4C5B-8C73-643AC9B424FA

Q30492652-F939291E-BD35-4799-82F8-B6A246EF3023

Q30492652-FB4A4CC6-AEFD-480B-BDF4-2E833BE6DF7F

P2860

Q30492652-03091DCA-0FA9-4425-A5E1-4BFFC935D22A

Q30492652-0DA97316-8D5D-4DDA-9D2C-82ED19BB02DD

Q30492652-1370514A-D1C9-43E3-B756-D840C59F7845

Q30492652-1B30B32C-5F4D-41C2-9F93-E1891754E672

Q30492652-1D8202DD-7197-4040-9DE1-B415D4A9CD5E

Q30492652-28F50115-F942-48D7-B3E1-93BC41ABF659

Q30492652-34312D5F-92CA-4EA2-97D0-A155549ADD03

Q30492652-3DF822A3-C297-433E-89C9-988C729F7E42

Q30492652-4978956C-80DE-40CB-94AD-925A6196173E

Q30492652-4A4BD8E1-C542-4D52-BFDB-1C078894339D

P2888

Q30492652-A6369A3B-D303-42C1-BBB3-8DB705C24ED4

P304

Q30492652-E3BBAAFA-D4CF-462D-BB7B-6149FDC1B1C6

P31

Q30492652-F1EB2A0D-9C0C-45CD-9315-E87B51D1FC20

P356

Q30492652-48444FBF-522F-46F5-AFC1-5B42B4C6CE01

P433

Q30492652-06682768-37B2-46C9-BD76-4B3494114469

P478

Q30492652-3955A9F5-79FA-48BC-8B6A-C74FE3199EF4

P50

Q30492652-be460bbe-454d-bd0d-846b-e9d49c513178

P577

Q30492652-754E91C8-16E1-4883-A941-A043FB07D5E8

P5875

Q30492652-941AFD77-6170-4964-B5B5-60FEA6D80872

P6179

Q30492652-338372D3-39CB-4CDE-9587-46D0CC49162F

P698

Q30492652-0BFDC0AD-BCFA-4D4F-8A43-37D7260549A9

P932

Q30492652-1E9D9DBA-C814-4789-A86D-E49F54766D77

P356

S10162-003-4020-3

P1433

P1476

Null mutation of alpha1D Ca2+ ...... t no vestibular defect in mice

@en

P2093

Ana E Vazquez

http://www.w3.org/2001/XMLSchema#string

Emma Lou Cardell

http://www.w3.org/2001/XMLSchema#string

Hanqi Chu

http://www.w3.org/2001/XMLSchema#string

Hee-Sup Shin

http://www.w3.org/2001/XMLSchema#string

Hongwei Dou

http://www.w3.org/2001/XMLSchema#string

Liping Nie

http://www.w3.org/2001/XMLSchema#string

Susan Parson

http://www.w3.org/2001/XMLSchema#string

Yoon Namkung

http://www.w3.org/2001/XMLSchema#string

P2860

Requirement for the L-type Ca(2+) channel alpha(1D) subunit in postnatal pancreatic beta cell generation

How the ear's works work

Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2

Different voltage-dependent inhibition by dihydropyridines of human Ca2+ channel splice variants

Chick cochlear hair cell exocytosis mediated by dihydropyridine-sensitive calcium channels

Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.

Calcium currents in hair cells isolated from semicircular canals of the frog.

Endogenous buffers limit the spread of free calcium in hair cells.

Kinetic analysis of barium currents in chick cochlear hair cells.

Physiological and morphological characterization of efferent neurones in the guinea pig cochlea.

P2888

s10162-003-4020-3

P304

215-226

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1007/S10162-003-4020-3

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

5

http://www.w3.org/2001/XMLSchema#string

P50

Ebenezer N. Yamoah

P577

2004-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8357470

http://www.w3.org/2001/XMLSchema#string

P6179

1000548303

http://www.w3.org/2001/XMLSchema#string

P698

15357422

http://www.w3.org/2001/XMLSchema#string

P932

2538408

http://www.w3.org/2001/XMLSchema#string