Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear
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Implications of the Hybrid Epithelial/Mesenchymal Phenotype in MetastasisEarly development of the vertebrate inner earSegregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control.Conditional gene expression in the mouse inner ear using Cre-loxP.Sensory hair cell development and regeneration: similarities and differencesWhere hearing starts: the development of the mammalian cochleaCanonical Notch signaling plays an instructive role in auditory supporting cell development.Regeneration of cone photoreceptors when cell ablation is primarily restricted to a particular cone subtypeCytoarchitecture of the mouse organ of corti from base to apex, determined using in situ two-photon imagingAn expanded Notch-Delta model exhibiting long-range patterning and incorporating MicroRNA regulationLead roles for supporting actors: critical functions of inner ear supporting cellsNotch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathwayAutophagy in the Vertebrate Inner Ear.Requirement for Jagged1-Notch2 signaling in patterning the bones of the mouse and human middle ear.Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea.Sensory hair cell regeneration in the zebrafish lateral line.Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochleaLMO4 functions as a negative regulator of sensory organ formation in the mammalian cochleaStem cell therapy for the inner ear: recent advances and future directions.Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration.Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochleaGeneration of human inner ear prosensory-like cells via epithelial-to-mesenchymal transition.In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.Concise review: Inner ear stem cells--an oxymoron, but why?Proliferative regeneration of zebrafish lateral line hair cells after different ototoxic insults.Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utriclesBiotechnology in the treatment of sensorineural hearing loss: foundations and future of hair cell regeneration.Inner ear hair cell-like cells from human embryonic stem cells.Reconstruction of the mouse otocyst and early neuroblast lineage at single-cell resolution.Numb is not a critical regulator of Notch-mediated cell fate decisions in the developing chick inner ear.Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti.NOTCH1 mediates a switch between two distinct secretomes during senescence.Characterization of Lgr5+ Progenitor Cell Transcriptomes after Neomycin Injury in the Neonatal Mouse CochleaArtificial induction of Sox21 regulates sensory cell formation in the embryonic chicken inner earSelective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.Jagged-Delta asymmetry in Notch signaling can give rise to a Sender/Receiver hybrid phenotype.N-myc controls proliferation, morphogenesis, and patterning of the inner earIn vivo Notch reactivation in differentiating cochlear hair cells induces Sox2 and Prox1 expression but does not disrupt hair cell maturation.Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner.Jagged mediates differences in normal and tumor angiogenesis by affecting tip-stalk fate decision.
P2860
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P2860
Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Notch signaling specifies pros ...... developing mammalian inner ear
@ast
Notch signaling specifies pros ...... developing mammalian inner ear
@en
type
label
Notch signaling specifies pros ...... developing mammalian inner ear
@ast
Notch signaling specifies pros ...... developing mammalian inner ear
@en
prefLabel
Notch signaling specifies pros ...... developing mammalian inner ear
@ast
Notch signaling specifies pros ...... developing mammalian inner ear
@en
P2860
P356
P1476
Notch signaling specifies pros ...... developing mammalian inner ear
@en
P2093
Byron H Hartman
Thomas A Reh
P2860
P304
15792-15797
P356
10.1073/PNAS.1002827107
P407
P577
2010-08-23T00:00:00Z