Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia. - Wikidata - wikimedia - TriplyDB

Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.

Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.

http://www.wikidata.org/entity/Q30496716

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Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction Progressive hearing loss and vestibular dysfunction caused by a homozygous nonsense mutation in CLIC5 Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins Autosomal recessive nonsyndromic deafness genes: a review Little but loud: small RNAs have a resounding affect on ear development Dynamic length regulation of sensory stereocilia Model membranes to shed light on the biochemical and physical properties of ezrin/radixin/moesin Gray matter NG2 cells display multiple Ca2+-signaling pathways and highly motile processes Organizing the cell cortex: the role of ERM proteins Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes Activated radixin is essential for GABAA receptor alpha5 subunit anchoring at the actin cytoskeleton Postnatal developmental expression of the PDZ scaffolds Na+ -H+ exchanger regulatory factors 1 and 2 in the rat cochlea Targeted knockout and lacZ reporter expression of the mouse Tmhs deafness gene and characterization of the hscy-2J mutation A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function QTL Mapping of Endocochlear Potential Differences between C57BL/6J and BALB/cJ mice.Noise-induced cochlear F-actin depolymerization is mediated via ROCK2/p-ERM signaling LKB1 Is Required for the Development and Maintenance of Stereocilia in Inner Ear Hair Cells in Mice.Genetics of auditory mechano-electrical transduction.Large membrane domains in hair bundles specify spatially constricted radixin activation.Characterization of a novel interaction between ELMO1 and ERM proteins.Actin in hair cells and hearing loss.Vezatin, an integral membrane protein of adherens junctions, is required for the sound resilience of cochlear hair cells.Mutations of the mouse ELMO domain containing 1 gene (Elmod1) link small GTPase signaling to actin cytoskeleton dynamics in hair cell stereocilia.Function and expression pattern of nonsyndromic deafness genes Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation.Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells.Shaping the intestinal brush border Emerging role for ERM proteins in cell adhesion and migration.Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI.Autosomal Recessive Nonsyndromic Hearing Impairment due to a Novel Deletion in the RDX Gene Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.Intracellular sphingosine kinase 2-derived sphingosine-1-phosphate mediates epidermal growth factor-induced ezrin-radixin-moesin phosphorylation and cancer cell invasion.Autosomal-Recessive Hearing Impairment Due to Rare Missense Variants within S1PR2 Trafficking and synaptic anchoring of ionotropic inhibitory neurotransmitter receptors.Ezrin/radixin/moesin proteins differentially regulate endothelial hyperpermeability after thrombin.Expression, localization, and binding activity of the ezrin/radixin/moesin proteins in the mouse testis.Cytoskeletal protein 4.1R negatively regulates T-cell activation by inhibiting the phosphorylation of LAT Auditory and vestibular hair cell stereocilia: relationship between functionality and inner ear disease.

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P2860

Radixin deficiency causes deafness associated with progressive degeneration of cochlear stereocilia.

http://www.wikidata.org/entity/Q30496716

description

2004 nî lūn-bûn

@nan

2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի օգոստոսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

Radixin deficiency causes deaf ...... ation of cochlear stereocilia.

@ast

Radixin deficiency causes deaf ...... ation of cochlear stereocilia.

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type

label

Radixin deficiency causes deaf ...... ation of cochlear stereocilia.

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Radixin deficiency causes deaf ...... ation of cochlear stereocilia.

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prefLabel

Radixin deficiency causes deaf ...... ation of cochlear stereocilia.

@ast

Radixin deficiency causes deaf ...... ation of cochlear stereocilia.

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Journal of Cell Biology

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Radixin deficiency causes deaf ...... ation of cochlear stereocilia.

@en

P2093

Hiroyuki Sasaki

http://www.w3.org/2001/XMLSchema#string

Juichi Ito

http://www.w3.org/2001/XMLSchema#string

Kanehisa Fukumoto

http://www.w3.org/2001/XMLSchema#string

Masaki Hata

http://www.w3.org/2001/XMLSchema#string

Sachiko Tsukita

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Shin-ichiro Kitajiri

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Shoichiro Tsukita

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Takayuki Nakagawa

http://www.w3.org/2001/XMLSchema#string

Tatsuya Katsuno

http://www.w3.org/2001/XMLSchema#string

P2860

Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells

Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin

NHE-RF, a regulatory cofactor for Na(+)-H+ exchange, is a common interactor for merlin and ERM (MERM) proteins

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.

Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity

cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein

The deaf jerker mouse has a mutation in the gene encoding the espin actin-bundling proteins of hair cell stereocilia and lacks espins.

Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

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559-570

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10.1083/JCB.200402007

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4

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166

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8397506

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15314067

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2172208

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