A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport
about
Charcot-Marie-Tooth disease and intracellular trafficA critical reevaluation of the stationary axonal cytoskeleton hypothesisSpastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP modelCryptic Amyloidogenic Elements in the 3' UTRs of Neurofilament Genes Trigger Axonal NeuropathyMutations in the motor and stalk domains of KIF5A in spastic paraplegia type 10 and in axonal Charcot-Marie-Tooth type 2.Neurofilaments are flexible polymers that often fold and unfold, but they move in a fully extended configuration.Severing and end-to-end annealing of neurofilaments in neurons.Abundant kif21b is associated with accelerated progression in neurodegenerative diseases.Axon diameter and axonal transport: In vivo and in vitro effects of androgens.FluoroMyelin™ Red is a bright, photostable and non-toxic fluorescent stain for live imaging of myelin.Object tracking with particle filtering in fluorescence microscopy images: application to the motion of neurofilaments in axonsNeurofilaments at a glance.Local regulation of neurofilament transport by myelinating cells.A novel mutation in KIF5A in a Malian family with spastic paraplegia and sensory loss.Role of kinesin-1 in the pathogenesis of SPG10, a rare form of hereditary spastic paraplegia.Neurogenetics of slow axonal transport: from cells to animals.The discontinuous nature of neurofilament transport accommodates both establishment and repair of the axonal neurofilament array.Toxic neurofilamentous axonopathies -- accumulation of neurofilaments and axonal degeneration.Neurofilaments and Neurofilament Proteins in Health and Disease.Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases.Axonal transport deficit in a KIF5A( -/- ) mouse model.Axonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features.Kymograph analysis with high temporal resolution reveals new features of neurofilament transport kinetics.Live-cell imaging of neurofilament transport in cultured neurons.VEGF Axonal Transport Dependent on Kinesin-1B and Microtubules Dynamics.Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.Axonal neurofilaments exhibit frequent and complex folding behaviors.Interference with kinesin-based anterograde neurofilament axonal transport increases neurofilament-neurofilament bundling.Hot-spot KIF5A mutations cause familial ALS
P2860
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P2860
A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A hereditary spastic paraplegi ...... srupts neurofilament transport
@ast
A hereditary spastic paraplegi ...... srupts neurofilament transport
@en
type
label
A hereditary spastic paraplegi ...... srupts neurofilament transport
@ast
A hereditary spastic paraplegi ...... srupts neurofilament transport
@en
prefLabel
A hereditary spastic paraplegi ...... srupts neurofilament transport
@ast
A hereditary spastic paraplegi ...... srupts neurofilament transport
@en
P2860
P356
P1476
A hereditary spastic paraplegi ...... srupts neurofilament transport
@en
P2093
P2860
P2888
P356
10.1186/1750-1326-5-52
P577
2010-11-18T00:00:00Z
P5875
P6179
1036443078