Evidence for three loci modifying age-at-onset of Alzheimer's disease in early-onset PSEN2 families.
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The genetic landscape of Alzheimer disease: clinical implications and perspectivesGenetic Modifiers of Age at Onset in Carriers of the G206A Mutation in PSEN1 With Familial Alzheimer Disease Among Caribbean Hispanics.Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2.Genome scan of age-at-onset in the NIMH Alzheimer disease sample uncovers multiple loci, along with evidence of both genetic and sample heterogeneity.Genome scan in familial late-onset Alzheimer's disease: a locus on chromosome 6 contributes to age-at-onsetGenome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOEExploratory data from complete genomes of familial alzheimer disease age-at-onset outliers.Genome scan for spelling deficits: effects of verbal IQ on models of transmission and trait gene localization.Estimation and visualization of identity-by-descent within pedigrees simplifies interpretation of complex trait analysis.Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease.Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease.CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease.Modifier variant of METTL13 suppresses human GAB1-associated profound deafness.
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P2860
Evidence for three loci modifying age-at-onset of Alzheimer's disease in early-onset PSEN2 families.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Evidence for three loci modify ...... in early-onset PSEN2 families.
@ast
Evidence for three loci modify ...... in early-onset PSEN2 families.
@en
type
label
Evidence for three loci modify ...... in early-onset PSEN2 families.
@ast
Evidence for three loci modify ...... in early-onset PSEN2 families.
@en
prefLabel
Evidence for three loci modify ...... in early-onset PSEN2 families.
@ast
Evidence for three loci modify ...... in early-onset PSEN2 families.
@en
P2093
P2860
P356
P1476
Evidence for three loci modify ...... in early-onset PSEN2 families.
@en
P2093
Chang-En Yu
Elisabeth Rosenthal
Ellen J Steinbart
Gerard D Schellenberg
Thomas D Bird
P2860
P304
P356
10.1002/AJMG.B.31072
P577
2010-07-01T00:00:00Z