Three clusters of conformational states in p450cam reveal a multistep pathway for closing of the substrate access channel.
about
A novel type of allosteric regulation: functional cooperativity in monomeric proteinsCrystal Structures of Substrate-Free and Nitrosyl Cytochrome P450cin: Implications for O 2 ActivationDouble electron-electron resonance shows cytochrome P450cam undergoes a conformational change in solution upon binding substrateConformational Adaptation of Human Cytochrome P450 2B6 and Rabbit Cytochrome P450 2B4 Revealed upon Binding Multiple Amlodipine MoleculesA Structural Snapshot of CYP2B4 in Complex with Paroxetine Provides Insights into Ligand Binding and Clusters of Conformational StatesP450cin Active Site Water: Implications for Substrate Binding and Solvent AccessibilitySynergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMRStructural differences between soluble and membrane bound cytochrome P450sHeme enzyme structure and function.Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.Active site diversification of P450cam with indole generates catalysts for benzylic oxidation reactionsA new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α,25-dihydroxyvitamin D₃.Coupling Oxygen Consumption with Hydrocarbon Oxidation in Bacterial Multicomponent Monooxygenases.Coupled flexibility change in cytochrome P450cam substrate binding determined by neutron scattering, NMR, and molecular dynamics simulationGeneral trends of dihedral conformational transitions in a globular protein.Oxygen activation and redox partner binding in cytochromes P450.Conformational Heterogeneity and the Affinity of Substrate Molecular Recognition by Cytochrome P450cam.Thermodynamics of camphor migration in cytochrome P450cam by atomistic simulations.Significant reduction in errors associated with nonbonded contacts in protein crystal structures: automated all-atom refinement with PrimeX.The dynamics of camphor in the cytochrome P450 CYP101D2.A short history of heme dioxygenases: rise, fall and rise again.The conformation of P450cam in complex with putidaredoxin is dependent on oxidation state.Versatile Trityl Spin Labels for Nanometer Distance Measurements on Biomolecules In Vitro and within Cells.Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage.Ligand Access Channels in Cytochrome P450 Enzymes: A Review.
P2860
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P2860
Three clusters of conformational states in p450cam reveal a multistep pathway for closing of the substrate access channel.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Three clusters of conformation ...... the substrate access channel.
@ast
Three clusters of conformation ...... the substrate access channel.
@en
type
label
Three clusters of conformation ...... the substrate access channel.
@ast
Three clusters of conformation ...... the substrate access channel.
@en
prefLabel
Three clusters of conformation ...... the substrate access channel.
@ast
Three clusters of conformation ...... the substrate access channel.
@en
P2093
P2860
P356
P1433
P1476
Three clusters of conformation ...... f the substrate access channel
@en
P2093
C David Stout
David B Goodin
Edith C Glazer
Richard F Wilson
P2860
P304
P356
10.1021/BI101726D
P407
P577
2011-01-11T00:00:00Z