A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain - Wikidata - wikimedia - TriplyDB

A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain

A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain

http://www.wikidata.org/entity/Q30498862

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The Synaptic Function of α-Synuclein Role of α- and β-Synucleins in the Axonal Pathology of Parkinson's Disease and Related Synucleinopathies Reducing synuclein accumulation improves neuronal survival after spinal cord injury Investigation of intramolecular dynamics and conformations of α-, β- and γ-synuclein Involvement of cholinergic system in hyperactivity in dopamine-deficient mice.Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of β-synuclein as a potential CHK physiological substrate.Combined immunotherapy with "anti-insulin resistance" therapy as a novel therapeutic strategy against neurodegenerative diseases.α-Synuclein expression selectively affects tumorigenesis in mice modeling Parkinson's disease.Disease-Modifying Effect of Adiponectin in Model of α-Synucleinopathies Bridging molecular genetics and biomarkers in lewy body and related disorders Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus.Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies.Toxic effects of human and rodent variants of alpha-synuclein in vivo.Possible alterations in β-Synuclein, the non-amyloidogenic homologue of α-Synuclein, during progression of sporadic α-synucleinopathies The neuropathology and cerebrovascular mechanisms of dementia Quantifying interactions of β-synuclein and γ-synuclein with model membranes Diversity of mitochondrial pathology in a mouse model of axonal degeneration in synucleinopathies.The loss of inhibitory C-terminal conformations in disease associated P123H β-synuclein α-Synuclein in Parkinson's disease.The function of α-synuclein.Alpha-, Beta-, and Gamma-synuclein Quantification in Cerebrospinal Fluid by Multiple Reaction Monitoring Reveals Increased Concentrations in Alzheimer's and Creutzfeldt-Jakob Disease but No Alteration in Synucleinopathies Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H β-synuclein.An exploratory analysis of γ-synuclein expression in endometrioid endometrial cancer.A pH-dependent switch promotes β-synuclein fibril formation via glutamate residues.Reply: To PMID 23536356.New brain-specific beta-synuclein isoforms show expression ratio changes in Lewy body diseases.Characterization of three synuclein genes in Xenopus laevis.Insight into the Dissociation of Behavior from Histology in Synucleinopathies and in Related Neurodegenerative Diseases.Critical appraisal of pathology transmission in the α-synuclein fibril model of Lewy body disorders.Delayed thalamic astrocytosis and disrupted sleep-wake patterns in a preclinical model of traumatic brain injury.Alternative Splicing of Alpha- and Beta-Synuclein Genes Plays Differential Roles in Synucleinopathies.Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein.Strain-independent global effect of hippocampal proteins in mice trained in the Morris water maze.Evolvability of Amyloidogenic Proteins in Human Brain.Dual effects of β-synuclein on the pathogenesis of Parkinson disease.Yeast reveals similar molecular mechanisms underlying alpha- and beta-synuclein toxicity.Sumoylation Protects Against β-Synuclein Toxicity in Yeast.Glucocerebrosidase mRNA is Diminished in Brain of Lewy Body Diseases and Changes with Disease Progression in Blood.Immature-like molecular expression patterns in the hippocampus of a mouse model of dementia with Lewy body-linked mutant β-synuclein.

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A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain

http://www.wikidata.org/entity/Q30498862

description

2010 nî lūn-bûn

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2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

A β-synuclein mutation linked ...... when expressed in mouse brain

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A β-synuclein mutation linked ...... when expressed in mouse brain

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type

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A β-synuclein mutation linked ...... when expressed in mouse brain

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A β-synuclein mutation linked ...... when expressed in mouse brain

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prefLabel

A β-synuclein mutation linked ...... when expressed in mouse brain

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A β-synuclein mutation linked ...... when expressed in mouse brain

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Nature Communications

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A β-synuclein mutation linked ...... when expressed in mouse brain

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Akio Sekigawa

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Albert R Laspada

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Jianshe Wei

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Kazunari Sekiyama

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Makoto Hashimoto

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Masaaki Nakai

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Masaaki Waragai

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Masayo Fujita

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Satoshi Inoue

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Shuei Sugama

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P2860

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

Beta-synuclein gene alterations in dementia with Lewy bodies.

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

Differential expression of secreted frizzled-related protein 4 in decidual cells during pregnancy

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy

The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases.

Gamma-synucleinopathy: neurodegeneration associated with overexpression of the mouse protein.

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.

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110

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10.1038/NCOMMS1101

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1

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Eliezer Masliah

Edward Rockenstein

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2010-11-02T00:00:00Z

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47661717

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1033929265

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21045828

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3060620

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