The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins. - Wikidata - wikimedia - TriplyDB

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

http://www.wikidata.org/entity/Q30500836

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Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival Under Pressure: Mechanical Stress Management in the Nucleus The Regulation of Cellular Responses to Mechanical Cues by Rho GTPases Focal adhesions, stress fibers and mechanical tension At the leading edge of three-dimensional cell migration Phosphorylation-mediated regulation of GEFs for RhoA From mechanical force to RhoA activation The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration Targeting and transport: how microtubules control focal adhesion dynamics Mechanosensitivity and compositional dynamics of cell-matrix adhesions Rho GAPs and GEFs: controling switches in endothelial cell adhesion Rgnef (p190RhoGEF) knockout inhibits RhoA activity, focal adhesion establishment, and cell motility downstream of integrins Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF.Interplay between Solo and keratin filaments is crucial for mechanical force-induced stress fiber reinforcement.Spatiotemporal dynamics of traction forces show three contraction centers in migratory neurons Endothelial Cells Use a Formin-Dependent Phagocytosis-Like Process to Internalize the Bacterium Listeria monocytogenes The focal adhesion-localized CdGAP regulates matrix rigidity sensing and durotaxis Breast cancer antiestrogen resistance 3 (BCAR3) promotes cell motility by regulating actin cytoskeletal and adhesion remodeling in invasive breast cancer cells.Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration ATRA mechanically reprograms pancreatic stellate cells to suppress matrix remodelling and inhibit cancer cell invasion.Automated NMR fragment based screening identified a novel interface blocker to the LARG/RhoA complex TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis Signaling pathways that control rho kinase activity maintain the embryonic epicardial progenitor state.E-cadherin-mediated force transduction signals regulate global cell mechanics Adhesion dynamics at a glance.To pull or be pulled: parsing the multiple modes of mechanotransduction.Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators.Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells.Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway CCM1-ICAP-1 complex controls β1 integrin-dependent endothelial contractility and fibronectin remodeling Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.ERK and phosphoinositide 3-kinase temporally coordinate different modes of actin-based motility during embryonic wound healing.Vinculin phosphorylation differentially regulates mechanotransduction at cell-cell and cell-matrix adhesions Haemodynamic and extracellular matrix cues regulate the mechanical phenotype and stiffness of aortic endothelial cells.TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion.F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling.A growth factor-induced, spatially organizing cytoskeletal module enables rapid and persistent fibroblast migration.RalB regulates contractility-driven cancer dissemination upon TGFβ stimulation via the RhoGEF GEF-H1 Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart.

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The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

http://www.wikidata.org/entity/Q30500836

description

2011 nî lūn-bûn

@nan

2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

@ast

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

@en

type

label

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

@ast

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

@en

prefLabel

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

@ast

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.

@en

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Nature Cell Biology

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The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

@en

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E Timothy O'Brien

http://www.w3.org/2001/XMLSchema#string

Keith Burridge

http://www.w3.org/2001/XMLSchema#string

Vinay Swaminathan

http://www.w3.org/2001/XMLSchema#string

P2860

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

Measurement of local viscoelasticity and forces in living cells by magnetic tweezers

Size-uniform 200 nm particles: fabrication and application to magnetofection

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

Regulation of cell motility by mitogen-activated protein kinase

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Matrix elasticity directs stem cell lineage specification

Tensional homeostasis and the malignant phenotype

Mammalian MAP kinase signalling cascades

Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

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10.1038/NCB2254

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6

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13

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Christophe Guilluy

Rafael Garcia-Mata

Richard Superfine

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2011-05-15T00:00:00Z

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51126926

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1029006148

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21572419

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3107386

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