Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response.
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Dynamic regulation of the COP9 signalosome in response to DNA damageNanoparticles for targeted delivery of therapeutics and small interfering RNAs in hepatocellular carcinomaProgress toward in vivo use of siRNAs-IIRecombinant human acid sphingomyelinase as an adjuvant to sorafenib treatment of experimental liver cancerAntitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2.Epigenetic upregulation of Bak by ZBP-89 inhibits the growth of hepatocellular carcinoma.Downregulation of Kinesin spindle protein inhibits proliferation, induces apoptosis and increases chemosensitivity in hepatocellular carcinoma cells.In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myelomaStem cells in liver diseases and cancer: recent advances on the path to new therapies.Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism.Short-interference RNAs: becoming medicines.THE COP9 SIGNALOSOME, A NOVEL, ESSENTIAL REGULATOR OF SKELETAL DEVELOPMENT AND TUMORIGENESIS.Hepatic stem cells and transforming growth factor β in hepatocellular carcinomaThe COP9 signalosome is required for autophagy, proteasome-mediated proteolysis, and cardiomyocyte survival in adult mice.Targeted inhibition of the COP9 signalosome for treatment of cancerHsa-miR-24-3p increases nasopharyngeal carcinoma radiosensitivity by targeting both the 3'UTR and 5'UTR of Jab1/CSN5.Down-regulation of the cyclin-dependent kinase inhibitor p57 is mediated by Jab1/Csn5 in hepatocarcinogenesis.The emerging roles of Jab1/CSN5 in cancer.Delivery strategies and potential targets for siRNA in major cancer typesKnockdown of Myosin VI Inhibits Proliferation of Hepatocellular Carcinoma Cells In Vitro.Roles of Multifunctional COP9 Signalosome Complex in Cell Fate and Implications for Drug Discovery.Nanoparticle-formulated siRNA targeting integrins inhibits hepatocellular carcinoma progression in mice.Structural biology: Corralling a protein-degradation regulator.Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5.Suppression of Jab1 expression inhibits proliferation and promotes apoptosis of AMC-HN-8 cells.Jab1/COPS5 as a Novel Biomarker for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Human Cancer.The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liverAzaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5
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P2860
Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Molecular targeting of CSN5 in ...... anism of therapeutic response.
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Molecular targeting of CSN5 in ...... anism of therapeutic response.
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type
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Molecular targeting of CSN5 in ...... anism of therapeutic response.
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Molecular targeting of CSN5 in ...... anism of therapeutic response.
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Molecular targeting of CSN5 in ...... anism of therapeutic response.
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Molecular targeting of CSN5 in ...... anism of therapeutic response.
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P2093
P2860
P356
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Molecular targeting of CSN5 in ...... anism of therapeutic response.
@en
P2093
E A Conner
I MacLachlan
J B Andersen
J U Marquardt
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P2888
P304
P356
10.1038/ONC.2011.126
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P577
2011-04-18T00:00:00Z
P5875
P6179
1036219792