Inhibition of aldose reductase prevents colon cancer metastasis - Wikidata - wikimedia - TriplyDB

Inhibition of aldose reductase prevents colon cancer metastasis

Inhibition of aldose reductase prevents colon cancer metastasis

http://www.wikidata.org/entity/Q30503931

about

An old NSAID revisited: crystal structure of aldose reductase in complex with sulindac at 1.0 Å supports a novel mechanism for its anticancer and antiproliferative effects Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design Structural Determinants of the Selectivity of 3-Benzyluracil-1-acetic Acids toward Human Enzymes Aldose Reductase and AKR1B10 Progress toward in vivo use of siRNAs-II Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice.Substrate Specificity, Inhibitor Selectivity and Structure-Function Relationships of Aldo-Keto Reductase 1B15: A Novel Human Retinaldehyde Reductase.Amelioration of Bleomycin-induced Pulmonary Fibrosis of Rats by an Aldose Reductase Inhibitor, Epalrestat.Aldose reductase inhibition suppresses azoxymethane-induced colonic premalignant lesions in C57BL/KsJ-db/db mice.4-Hydroxynonenal in the pathogenesis and progression of human diseases.Critical analysis of carcinogenicity study outcomes. Relationship with pharmacological properties.SDF-1/CXCR4 axis promotes directional migration of colorectal cancer cells through upregulation of integrin αvβ6.Preventive cancer stem cell-based vaccination reduces liver metastasis development in a rat colon carcinoma syngeneic model.Expression of the Aldo-Ketoreductases AKR1B1 and AKR1B10 in Human Cancers Aldose reductase inhibition suppresses colon cancer cell viability by modulating microRNA-21 mediated programmed cell death 4 (PDCD4) expression Aldose reductase inhibition enhances TRAIL-induced human colon cancer cell apoptosis through AKT/FOXO3a-dependent upregulation of death receptors.Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity.Aldose reductase inhibitor, fidarestat regulates mitochondrial biogenesis via Nrf2/HO-1/AMPK pathway in colon cancer cells.The use of dimethylsulfoxide as a solvent in enzyme inhibition studies: the case of aldose reductase.Aldose reductase inhibitor, fidarestat prevents doxorubicin-induced endothelial cell death and dysfunction.Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.Aldose reductase inhibitor, fidarestat prevents high-fat diet-induced intestinal polyps in ApcMin/+ mice.

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Inhibition of aldose reductase prevents colon cancer metastasis

http://www.wikidata.org/entity/Q30503931

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Inhibition of aldose reductase prevents colon cancer metastasis

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Inhibition of aldose reductase prevents colon cancer metastasis

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type

label

Inhibition of aldose reductase prevents colon cancer metastasis

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Inhibition of aldose reductase prevents colon cancer metastasis

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prefLabel

Inhibition of aldose reductase prevents colon cancer metastasis

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Inhibition of aldose reductase prevents colon cancer metastasis

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Inhibition of aldose reductase prevents colon cancer metastasis

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Aramati B M Reddy

http://www.w3.org/2001/XMLSchema#string

Ashish Saxena

http://www.w3.org/2001/XMLSchema#string

B Mark Evers

http://www.w3.org/2001/XMLSchema#string

Ravinder Tammali

http://www.w3.org/2001/XMLSchema#string

Sanjay Awasthi

http://www.w3.org/2001/XMLSchema#string

Satish K Srivastava

http://www.w3.org/2001/XMLSchema#string

Suimin Qiu

http://www.w3.org/2001/XMLSchema#string

P2860

Aldose reductase regulates TNF-alpha-induced PGE2 production in human colon cancer cells

Nuclear transcription factor-kappaB as a target for cancer drug development

Mitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growth

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

Role of angiogenesis in tumor growth and metastasis

Cancer metastasis: building a framework

In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

Role of the tumor microenvironment in mediating response to anti-angiogenic therapy.

Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options.

Inhibition of carcinogenesis by tea.

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1259-1267

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scholarly article

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10.1093/CARCIN/BGR102

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8

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32

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Piotr G Rychahou

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2011-06-03T00:00:00Z

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51192621

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21642355

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3166198

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