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Dissection of Pol II trigger loop function and Pol II activity-dependent control of start site selection in vivoThe RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitinInteraction between transcription elongation factors and mRNA 3'-end formation at the Saccharomyces cerevisiae GAL10-GAL7 locus.Transcription elongation factors repress transcription initiation from cryptic sites.Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation.The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoADivergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and IITranscription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms.The architecture of RNA polymerase fidelityWide-ranging and unexpected consequences of altered Pol II catalytic activity in vivo.A dual interface determines the recognition of RNA polymerase II by RNA capping enzyme.Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis.A bridge to transcription by RNA polymerase.Relationships of RNA polymerase II genetic interactors to transcription start site usage defects and growth in Saccharomyces cerevisiae.The Histone Chaperones FACT and Spt6 Restrict H2A.Z from Intragenic Locations.Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.Activation and reactivation of the RNA polymerase II trigger loop for intrinsic RNA cleavage and catalysis.Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.RNA Polymerase II Trigger Loop Mobility: INDIRECT EFFECTS OF Rpb9.Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae.RNAs nonspecifically inhibit RNA polymerase II by preventing binding to the DNA templateBasic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.Spt5 and spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster.Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3'-untranslated region.Uncoupling Promoter Opening from Start-Site Scanning.From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.Helicase activity is only partially required for Schizosaccharomyces pombe Rqh1p function.Competing for the clamp: promoting RNA polymerase processivity and managing the transition from initiation to elongation.Pairs of promoter pairs in a web of transcription.High-resolution and high-accuracy topographic and transcriptional maps of the nucleosome barrierPerturbations of Transcription and Gene Expression-Associated Processes Alter Distribution of Cell Size Values in Saccharomyces cerevisiaeSpecialized RSC: Substrate Specificities for a Conserved Chromatin RemodelerUniversal promoter scanning by Pol II during transcription initiation in Saccharomyces cerevisiae
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Craig D Kaplan
@nl
Craig D Kaplan
@sl
Craig D. Kaplan
@en
Craig D. Kaplan
@es
Craig Kaplan
@fr
type
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Craig D Kaplan
@nl
Craig D Kaplan
@sl
Craig D. Kaplan
@en
Craig D. Kaplan
@es
Craig Kaplan
@fr
altLabel
Craig Kaplan
@en
prefLabel
Craig D Kaplan
@nl
Craig D Kaplan
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Craig D. Kaplan
@en
Craig D. Kaplan
@es
Craig Kaplan
@fr
P108
P106
P1153
7103380214
P21
P31
P496
0000-0002-7518-695X