Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment - Wikidata - wikimedia - TriplyDB

Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment

Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment

http://www.wikidata.org/entity/Q30514797

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Beyond the Niche: Myelodysplastic Syndrome Topobiology in the Laboratory and in the Clinic Humanized hemato-lymphoid system mice A hostel for the hostile: the bone marrow niche in hematologic neoplasms Oxygen sensing mesenchymal progenitors promote neo-vasculogenesis in a humanized mouse model in vivo Bone Marrow Blood Vessels: Normal and Neoplastic Niche Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth.Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation.Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.Blood and immune cell engineering: Cytoskeletal contractility and nuclear rheology impact cell lineage and localization: Biophysical regulation of hematopoietic differentiation and trafficking.Histone Deacetylase Inhibitors Target the Leukemic Microenvironment by Enhancing a Nherf1-Protein Phosphatase 1α-TAZ Signaling Pathway in Osteoblasts Engineering of a functional bone organ through endochondral ossification Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy.Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes.CXCR4 downregulation of let-7a drives chemoresistance in acute myeloid leukemia.Connective tissue growth factor regulates adipocyte differentiation of mesenchymal stromal cells and facilitates leukemia bone marrow engraftment.Bone marrow niche-mediated survival of leukemia stem cells in acute myeloid leukemia: Yin and Yang.HIF-1α inhibition by 2-methoxyestradiol induces cell death via activation of the mitochondrial apoptotic pathway in acute myeloid leukemia.Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network.Wnt pathway contributes to the protection by bone marrow stromal cells of acute lymphoblastic leukemia cells and is a potential therapeutic target.Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates.Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance.Normal and leukemic stem cell niches: insights and therapeutic opportunities.Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impact.The human and murine hematopoietic stem cell niches: are they comparable?Bioengineering of Humanized Bone Marrow Microenvironments in Mouse and Their Visualization by Live Imaging.Versatile humanized niche model enables study of normal and malignant human hematopoiesis.Notch ligand Delta-like 1 promotes in vivo vasculogenesis in human cord blood-derived endothelial colony forming cells.An engineered multicomponent bone marrow niche for the recapitulation of hematopoiesis at ectopic transplantation sites.4th international conference on tumor progression and therapeutic resistance: meeting report.In vivo engineering of bone tissues with hematopoietic functions and mixed chimerism.A humanised tissue-engineered bone model allows species-specific breast cancer-related bone metastasis in vivo.Generation and use of a humanized bone-marrow-ossicle niche for hematopoietic xenotransplantation into mice.Engineering a humanized bone organ model in mice to study bone metastases.Concise Review: Adaptation of the Bone Marrow Stroma in Hematopoietic Malignancies: Current Concepts and Models.Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches.Role of the microenvironment in myeloid malignancies.Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival.The use of humanized mice for studies of viral pathogenesis and immunity.

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Human extramedullary bone marrow in mice: a novel in vivo model of genetically controlled hematopoietic microenvironment

http://www.wikidata.org/entity/Q30514797

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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Human extramedullary bone marr ...... hematopoietic microenvironment

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Human extramedullary bone marr ...... hematopoietic microenvironment

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Andreas Reinisch

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Dirk Strunk

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Nicole A Hofmann

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Rodrigo Jacamo

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Rui-yu Wang

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Venkata Lokesh Battula

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Ye Chen

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Yue-xi Shi

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P2860

Multilineage potential of adult human mesenchymal stem cells

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche

Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

Identification of the haematopoietic stem cell niche and control of the niche size

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches.

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Marina Konopleva

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