Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis.
about
Genome-wide prediction and validation of peptides that bind human prosurvival Bcl-2 proteinsThe TRPM7 chanzyme is cleaved to release a chromatin-modifying kinaseTransient receptor potential (TRP) channels and cardiac fibrosisTRPM7 and its role in neurodegenerative diseasesEmerging roles of L-type voltage-gated and other calcium channels in T lymphocytesIn vivo imaging of hierarchical spatiotemporal activation of caspase-8 during apoptosisTranslocation of mixed lineage kinase domain-like protein to plasma membrane leads to necrotic cell deathTRPM7The puzzle of TRPV4 channelopathies.TRPM6 kinase activity regulates TRPM7 trafficking and inhibits cellular growth under hypomagnesic conditions.MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines.TRPM7 regulates vascular endothelial cell adhesion and tube formation.Activation of TRPM7 channels by small molecules under physiological conditions.Transient Receptor Potential Melastatin 7 Cation Channel Kinase: New Player in Angiotensin II-Induced Hypertension.Ion channels in innate and adaptive immunityTRPM7 is regulated by halides through its kinase domainIon channel-kinase TRPM7 is required for maintaining cardiac automaticity.Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases.Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke?Oncogenic role and therapeutic target of transient receptor potential melastatin 7 channel in malignancy.Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer.Natural and Synthetic Modulators of the TRPM7 Channel.Redox-sensitive transient receptor potential channels in oxygen sensing and adaptation.Transient Receptor Potential (TRP) channels in T cells.What is the evidence for the role of TRP channels in inflammatory and immune cells?Ion channels in regulated cell death.Zinc transport and the inhibition of the L-type calcium channel are two separable functions of ZnT-1.TRPM7 kinase activity regulates murine mast cell degranulation.The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity.Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides.Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization.TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles.FTY-720 induces apoptosis in neuroblastoma via multiple signaling pathways.The TRPM7 channel kinase regulates store-operated calcium entry.Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.Inactivation of TRPM7 kinase in mice results in enlarged spleens, reduced T-cell proliferation and diminished store-operated calcium entry.Following OGD/R, annexin 1 nuclear translocation and subsequent induction of apoptosis in neurons are assisted by myosin IIA in a TRPM7 kinase-dependent manner.TNFα induces Ca2+ influx to accelerate extrinsic apoptosis in hepatocellular carcinoma cells.Mibefradil represents a new class of benzimidazole TRPM7 channel agonists.Structural biology of TRP channels
P2860
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P2860
Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Cleavage of TRPM7 releases the ...... tion in Fas-induced apoptosis.
@ast
Cleavage of TRPM7 releases the ...... tion in Fas-induced apoptosis.
@en
type
label
Cleavage of TRPM7 releases the ...... tion in Fas-induced apoptosis.
@ast
Cleavage of TRPM7 releases the ...... tion in Fas-induced apoptosis.
@en
prefLabel
Cleavage of TRPM7 releases the ...... tion in Fas-induced apoptosis.
@ast
Cleavage of TRPM7 releases the ...... tion in Fas-induced apoptosis.
@en
P2093
P2860
P50
P1433
P1476
Cleavage of TRPM7 releases the ...... tion in Fas-induced apoptosis.
@en
P2093
Anirudh Penumaka
Grigory Krapivinsky
I Scott Ramsey
Luba Krapivinsky
Markus Delling
Sebastien Febvay
Yunona Manasian
P2860
P304
P356
10.1016/J.DEVCEL.2012.04.006
P407
P577
2012-06-01T00:00:00Z