Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation. - Wikidata - wikimedia - TriplyDB

Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.

Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.

http://www.wikidata.org/entity/Q30528108

about

Kinesin-5: cross-bridging mechanism to targeted clinical therapy Regulation of the centrosome cycle The Ran Pathway in Drosophila melanogaster Mitosis Cdk1 Activates Pre-mitotic Nuclear Envelope Dynein Recruitment and Apical Nuclear Migration in Neural Stem Cells Functions and mechanics of dynein motor proteins Mechanical dynamics in live cells and fluorescence-based force/tension sensors The tetrameric kinesin Kif25 suppresses pre-mitotic centrosome separation to establish proper spindle orientation.Kinesin-12 differentially affects spindle assembly depending on its microtubule substrate EGF-induced centrosome separation promotes mitotic progression and cell survival.Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanism Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion.A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes.Assembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1 Kinesin-5 inhibitor resistance is driven by kinesin-12 Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics.Astral microtubules control redistribution of dynein at the cell cortex to facilitate spindle positioning.Mechanism and regulation of kinesin-5, an essential motor for the mitotic spindle.Centrosome dynamics as a source of chromosomal instability The centrosomal linker and microtubules provide dual levels of spatial coordination of centrosomes.Lamins position the nuclear pores and centrosomes by modulating dynein.Chronic Exposure to Particulate Chromate Induces Premature Centrosome Separation and Centriole Disengagement in Human Lung Cells.Systematic dissection of dynein regulators in mitosis Cytoplasmic dynein crosslinks and slides anti-parallel microtubules using its two motor domains.N-Acetyl-D-Glucosamine Kinase Interacts with Dynein-Lis1-NudE1 Complex and Regulates Cell Division.SUN proteins facilitate the removal of membranes from chromatin during nuclear envelope breakdown.The molecular basis for kinesin functional specificity during mitosis.Therapeutic applications of carbon nanotubes: opportunities and challenges.Function and regulation of dynein in mitotic chromosome segregation.Separate to operate: control of centrosome positioning and separation.Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment Mechanisms and functions of nuclear envelope remodelling.Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation.Nuclear envelope-associated dynein cooperates with Eg5 to drive prophase centrosome separation.Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15-dependent drug resistance Resistance is not futile: Surviving Eg5 inhibition.Dynein recruitment to nuclear pores activates apical nuclear migration and mitotic entry in brain progenitor cells.PKCε Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly.Sequential activities of Dynein, Mud and Asp in centrosome-spindle coupling maintain centrosome number upon mitosis.Computer simulations reveal mechanisms that organize nuclear dynein forces to separate centrosomes.Intercentrosomal angular separation during mitosis plays a crucial role for maintaining spindle stability.

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Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.

http://www.wikidata.org/entity/Q30528108

description

2012 nî lūn-bûn

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2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Nuclear envelope-associated dy ...... ent bipolar spindle formation.

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Nuclear envelope-associated dy ...... ent bipolar spindle formation.

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type

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Nuclear envelope-associated dy ...... ent bipolar spindle formation.

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Nuclear envelope-associated dy ...... ent bipolar spindle formation.

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Nuclear envelope-associated dy ...... ent bipolar spindle formation.

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Nuclear envelope-associated dy ...... ent bipolar spindle formation.

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P1433

The EMBO Journal

P1476

Nuclear envelope-associated dy ...... ent bipolar spindle formation.

@en

P2093

Belen Fernandez-Garcia

http://www.w3.org/2001/XMLSchema#string

Erica F Geers

http://www.w3.org/2001/XMLSchema#string

Johnathan L Meaders

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Marvin E Tanenbaum

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Roy G H P van Heesbeen

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P2860

The Polo kinase Plk4 functions in centriole duplication

Nek9 is a Plk1-activated kinase that controls early centrosome separation through Nek6/7 and Eg5

Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

Cytoplasmic dynein plays a role in mammalian mitotic spindle formation

Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex

A bipolar kinesin

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

Directional switching of the kinesin Cin8 through motor coupling.

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4179-4190

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scholarly article

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10.1038/EMBOJ.2012.272

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21

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31

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René H. Medema

Jonne Raaijmakers

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2012-10-02T00:00:00Z

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232008766

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23034402

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3492733

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