A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis - Wikidata - wikimedia - TriplyDB

A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis

A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis

http://www.wikidata.org/entity/Q30535900

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Endothelial Plasticity: Shifting Phenotypes through Force Feedback Novel mechanisms of endothelial mechanotransduction Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents ERK5 Mediated Signalling in Diabetic Retinopathy Covalent docking of large libraries for the discovery of chemical probes De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.Mechanistic elucidation of the antitumor properties of withaferin a in breast cancer.The arterial microenvironment: the where and why of atherosclerosis.LRP-1: functions, signaling and implications in kidney and other diseases.Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function.Kinase analysis in alcoholic hepatitis identifies p90RSK as a potential mediator of liver fibrogenesis Platelet Extracellular Regulated Protein Kinase 5 Is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct Expansion Oxidized LDL induces FAK-dependent RSK signaling to drive NF-κB activation and VCAM-1 expression Kinase-SUMO networks in diabetes-mediated cardiovascular disease.Molecular biology of atherosclerosis.Shear stress and atherosclerosis Targeting protein kinases with selective and semipromiscuous covalent inhibitors.CHOP Deficiency Ameliorates ERK5 Inhibition-Mediated Exacerbation of Streptozotocin-Induced Hyperglycemia and Pancreatic β-Cell Apoptosis.Ribosomal S6 kinase (RSK) modulators: a patent review.Blood Brothers: Hemodynamics and Cell-Matrix Interactions in Endothelial Function.Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events.Flow signaling and atherosclerosis.Sub-cellular localization specific SUMOylation in the heart.Coordination of Cellular Localization-Dependent Effects of Sumoylation in Regulating Cardiovascular and Neurological Diseases.Novel insights in the metabolic syndrome-induced oxidative stress and inflammation-mediated atherosclerosis.17β-Estradiol and/or estrogen receptor alpha blocks isoproterenol-induced calcium accumulation and hypertrophy via GSK3β/PP2A/NFAT3/ANP pathway.Flow pattern-dependent endothelial cell responses through transcriptional regulation.En Face Preparation of Mouse Blood Vessels.Erk5 inhibits endothelial migration via KLF2-dependent down-regulation of PAK1.Developing a Reliable Mouse Model for Cancer Therapy-Induced Cardiovascular Toxicity in Cancer Patients and Survivors.Ionizing Radiation Induces Endothelial Inflammation and Apoptosis via p90RSK-Mediated ERK5 S496 Phosphorylation.Ponatinib Activates an Inflammatory Response in Endothelial Cells via ERK5 SUMOylation

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A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis

http://www.wikidata.org/entity/Q30535900

description

2012 nî lūn-bûn

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2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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A crucial role for p90RSK-medi ...... ysfunction and atherosclerosis

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A crucial role for p90RSK-medi ...... ysfunction and atherosclerosis

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Carolyn McClain

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Chang-Hoon Woo

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Cheryl Hurley

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Craig Morrell

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Eugene Chang

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Faqian Li

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Hakjoo Lee

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Haodong Xu

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Iana M Serafimova

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Jack Taunton

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P2860

Atherosclerosis

ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression

Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress

Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells.

Mechanisms underlying endothelial dysfunction in diabetes mellitus.

Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation.

Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands.

ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain

Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

Activation of protein kinase C isoforms and its impact on diabetic complications.

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486-499

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10.1161/CIRCULATIONAHA.112.116988

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4

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233931607

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23243209

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atherosclerosis

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3574639

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