The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes.
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Mutations in ZMYND10, a gene essential for proper axonemal assembly of inner and outer dynein arms in humans and flies, cause primary ciliary dyskinesiaThe awesome power of dikaryons for studying flagella and basal bodies in Chlamydomonas reinhardtiiMutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human DiseaseCCDC65 mutation causes primary ciliary dyskinesia with normal ultrastructure and hyperkinetic ciliaLoss-of-Function GAS8 Mutations Cause Primary Ciliary Dyskinesia and Disrupt the Nexin-Dynein Regulatory ComplexThe neomuran revolution and phagotrophic origin of eukaryotes and cilia in the light of intracellular coevolution and a revised tree of lifeCMF22 is a broadly conserved axonemal protein and is required for propulsive motility in Trypanosoma brucei.FAP20 is an inner junction protein of doublet microtubules essential for both the planar asymmetrical waveform and stability of flagella in ChlamydomonasMotility and more: the flagellum of Trypanosoma brucei.Cryo-electron tomography of motile cilia and flagellaThe CSC proteins FAP61 and FAP251 build the basal substructures of radial spoke 3 in ciliaDRC3 connects the N-DRC to dynein g to regulate flagellar waveform.The role of the dynein light intermediate chain in retrograde IFT and flagellar function in Chlamydomonas.The nexin link and B-tubule glutamylation maintain the alignment of outer doublets in the ciliary axoneme.Evolution of Cilia.IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium.TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa.Cryo-electron tomography reveals ciliary defects underlying human RSPH1 primary ciliary dyskinesia.Detailed structural and biochemical characterization of the nexin-dynein regulatory complexIn situ localization of N and C termini of subunits of the flagellar nexin-dynein regulatory complex (N-DRC) using SNAP tag and cryo-electron tomography.A NIMA-Related Kinase Suppresses the Flagellar Instability Associated with the Loss of Multiple Axonemal Structures.The ciliary inner dynein arm, I1 dynein, is assembled in the cytoplasm and transported by IFT before axonemal docking.A Structural Basis for How Motile Cilia BeatPrimary ciliary dyskinesia and associated sensory ciliopathiesMutations in Dnaaf1 and Lrrc48 Cause Hydrocephalus, Laterality Defects, and Sinusitis in Mice.Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia.A differential cargo-loading model of ciliary length regulation by IFT.Methods for Studying Movement of Molecules Within Cilia.Protein transport in growing and steady-state cilia.Axoneme Structure from Motile Cilia.High-Resolution Profiling of a Synchronized Diurnal Transcriptome from Chlamydomonas reinhardtii Reveals Continuous Cell and Metabolic Differentiation.Alcohol-induced ciliary dysfunction targets the outer dynein arm.Electrostatic interaction between polyglutamylated tubulin and the nexin-dynein regulatory complex regulates flagellar motility.A molecular ruler determines the repeat length in eukaryotic cilia and flagella.Flagellar central pair assembly in Chlamydomonas reinhardtii.DRC2/CCDC65 is a central hub for assembly of the nexin-dynein regulatory complex and other regulators of ciliary and flagellar motility.Flagellar incorporation of proteins follows at least two different routes in trypanosomes.Value of transmission electron microscopy for primary ciliary dyskinesia diagnosis in the era of molecular medicine: Genetic defects with normal and non-diagnostic ciliary ultrastructure.Ciliary Motility: Regulation of Axonemal Dynein Motors.
P2860
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P2860
The N-DRC forms a conserved biochemical complex that maintains outer doublet alignment and limits microtubule sliding in motile axonemes.
description
2013 nî lūn-bûn
@nan
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The N-DRC forms a conserved bi ...... le sliding in motile axonemes.
@ast
The N-DRC forms a conserved bi ...... le sliding in motile axonemes.
@en
type
label
The N-DRC forms a conserved bi ...... le sliding in motile axonemes.
@ast
The N-DRC forms a conserved bi ...... le sliding in motile axonemes.
@en
prefLabel
The N-DRC forms a conserved bi ...... le sliding in motile axonemes.
@ast
The N-DRC forms a conserved bi ...... le sliding in motile axonemes.
@en
P2093
P2860
P356
P1476
The N-DRC forms a conserved bi ...... le sliding in motile axonemes.
@en
P2093
Catherine A Perrone
Douglas Tritschler
Joshua Mueller
Kristyn Vanderwaal
M E Porter
Raqual Bower
Winfield S Sale
P2860
P304
P356
10.1091/MBC.E12-11-0801
P577
2013-02-20T00:00:00Z