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The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

http://www.wikidata.org/entity/Q30538972

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Regulation of mammalian transcription and splicing by Nuclear RNAi Biogenesis, turnover, and mode of action of plant microRNAs Single molecule fluorescence approaches shed light on intracellular RNAs The panorama of miRNA-mediated mechanisms in mammalian cells Visualizing lipid-formulated siRNA release from endosomes and target gene knockdown.A new role for the GARP complex in microRNA-mediated gene regulation Membrane-association of mRNA decapping factors is independent of stress in budding yeast.RNAi factors are present and active in human cell nuclei Synaptotagmin 11 interacts with components of the RNA-induced silencing complex RISC in clonal pancreatic β-cells RNA-mediated degradation of microRNAs: A widespread viral strategy?Trans-acting small interfering RNA4: key to nutraceutical synthesis in grape development?Obstacles and opportunities in the functional analysis of extracellular vesicle RNA - an ISEV position paper Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER Visualization of self-delivering hydrophobically modified siRNA cellular internalization.Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma.Dephosphorylation of tyrosine 393 in argonaute 2 by protein tyrosine phosphatase 1B regulates gene silencing in oncogenic RAS-induced senescence.Multifunctional roles for the protein translocation machinery in RNA anchoring to the endoplasmic reticulum.Traffic into silence: endomembranes and post-transcriptional RNA silencing.Mature miRNAs form secondary structure, which suggests their function beyond RISC.Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading.dsRNA binding protein PACT/RAX in gene silencing, development and diseases.Identification of AGO3-associated miRNAs and computational prediction of their targets in the green alga Chlamydomonas reinhardtii.Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs.Diversity and selectivity in mRNA translation on the endoplasmic reticulum miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets.Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors.The Whereabouts of microRNA Actions: Cytoplasm and Beyond.Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.Poly-Cross-Linked PEI Through Aromatically Conjugated Imine Linkages as a New Class of pH-Responsive Nucleic Acids Packing Cationic Polymers.TLR9-Targeted SiRNA Delivery In Vivo PDL1 Regulation by p53 via miR-34 Stable association of RNAi machinery is conserved between the cytoplasm and nucleus of human cells.Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling.Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulum Dextran functionalization enhances nanoparticle-mediated siRNA delivery and silencing.Trip to ER: MicroRNA-mediated translational repression in plants.Timescales and bottlenecks in miRNA-dependent gene regulation.Biogenesis of phased siRNAs on membrane-bound polysomes in Arabidopsis.The conserved SNARE SEC-22 localizes to late endosomes and negatively regulates RNA interference in Caenorhabditis elegans.Differential RISC association of endogenous human microRNAs predicts their inhibitory potential.

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P2860

The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing

http://www.wikidata.org/entity/Q30538972

description

2013 nî lūn-bûn

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2013 թուականի Մարտին հրատարակուած գիտական յօդուած

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2013 թվականի մարտին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing

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The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing

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type

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The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing

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The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing

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The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing

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The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing

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The EMBO Journal

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The rough endoplasmatic reticu ...... f siRNA-mediated RNA silencing

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P2093

Anja Fritzsche

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David V Morrissey

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Dominic Trojer

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Jan Weiler

http://www.w3.org/2001/XMLSchema#string

Joel Wirz

http://www.w3.org/2001/XMLSchema#string

Justin Hean

http://www.w3.org/2001/XMLSchema#string

Lukas Stalder

http://www.w3.org/2001/XMLSchema#string

Martin Hintersteiner

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Nicole C Meisner-Kober

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Pascal Basselet

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P2860

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

A human, ATP-independent, RISC assembly machine fueled by pre-miRNA

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA

In vitro reconstitution of the human RISC-loading complex

Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer

TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing

ATP-dependent human RISC assembly pathways

Cleavage of the siRNA passenger strand during RISC assembly in human cells

GERp95, a membrane-associated protein that belongs to a family of proteins involved in stem cell differentiation

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1115-1127

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scholarly article

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10.1038/EMBOJ.2013.52

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8

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32

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Florian Aeschimann

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2013-03-19T00:00:00Z

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236064181

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23511973

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3630355

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