Selective forelimb impairment in rats expressing a pathological TDP-43 25 kDa C-terminal fragment to mimic amyotrophic lateral sclerosis.

Selective forelimb impairment in rats expressing a pathological TDP-43 25 kDa C-terminal fragment to mimic amyotrophic lateral sclerosis.

Item
http://www.wikidata.org/entity/Q30541190
The extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivoReversible behavioral phenotypes in a conditional mouse model of TDP-43 proteinopathiesInitial gene vector dosing for studying symptomatology of amyotrophic lateral sclerosis in non-human primates.Valproate Attenuates 25-kDa C-Terminal Fragment of TDP-43-Induced Neuronal Toxicity via Suppressing Endoplasmic Reticulum Stress and Activating Autophagy.Rodent Models of Amyotrophic Lateral SclerosisAAV9 supports wide-scale transduction of the CNS and TDP-43 disease modeling in adult rats.Severe respiratory changes at end stage in a FUS-induced disease state in adult rats.Preservation of forelimb function by UPF1 gene therapy in a rat model of TDP-43-induced motor paralysis.An insoluble frontotemporal lobar degeneration-associated TDP-43 C-terminal fragment causes neurodegeneration and hippocampus pathology in transgenic miceDisease animal models of TDP-43 proteinopathy and their pre-clinical applications.Better Targeting, Better Efficiency for Wide-Scale Neuronal Transduction with the Synapsin Promoter and AAV-PHP.B.Methods and Tips for Intravenous Administration of Adeno-associated Virus to Rats and Evaluation of Central Nervous System Transduction.Adenoviral expression of TDP-43 and FUS genes and shRNAs for protein degradation pathways in rodent motoneurons in vitro and in vivo.TDP43 and RNA instability in amyotrophic lateral sclerosis.TDP43 nuclear export and neurodegeneration in models of amyotrophic lateral sclerosis and frontotemporal dementia.Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization.
P2860

Selective forelimb impairment in rats expressing a pathological TDP-43 25 kDa C-terminal fragment to mimic amyotrophic lateral sclerosis.

Item
http://www.wikidata.org/entity/Q30541190
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Selective forelimb impairment ...... amyotrophic lateral sclerosis.
@ast
Selective forelimb impairment ...... amyotrophic lateral sclerosis.
@en
type
label
Selective forelimb impairment ...... amyotrophic lateral sclerosis.
@ast
Selective forelimb impairment ...... amyotrophic lateral sclerosis.
@en
prefLabel
Selective forelimb impairment ...... amyotrophic lateral sclerosis.
@ast
Selective forelimb impairment ...... amyotrophic lateral sclerosis.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Selective forelimb impairment ...... amyotrophic lateral sclerosis.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P932