Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.
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Nephropathic cystinosis: an international consensus documentEndo-lysosomal dysfunction in human proximal tubular epithelial cells deficient for lysosomal cystine transporter cystinosinCystinosis (ctns) zebrafish mutant shows pronephric glomerular and tubular dysfunction.Time course of pathogenic and adaptation mechanisms in cystinotic mouse kidneysImpairment of chaperone-mediated autophagy leads to selective lysosomal degradation defects in the lysosomal storage disease cystinosisA mouse model suggests two mechanisms for thyroid alterations in infantile cystinosis: decreased thyroglobulin synthesis due to endoplasmic reticulum stress/unfolded protein response and impaired lysosomal processing.Rab27a/Slp2-a complex is involved in Schwann cell myelination.Lysosome dysfunction in the pathogenesis of kidney diseases.The renal Fanconi syndrome in cystinosis: pathogenic insights and therapeutic perspectives.Lysosomal cystine accumulation promotes mitochondrial depolarization and induction of redox-sensitive genes in human kidney proximal tubular cells.Receptor-Mediated Endocytosis in the Proximal Tubule.Identification of Neutrophil Exocytosis Inhibitors (Nexinhibs), Small Molecule Inhibitors of Neutrophil Exocytosis and Inflammation: DRUGGABILITY OF THE SMALL GTPase Rab27a.The role of cold-inducible RNA binding protein in cell stress response.Cystinosin, the small GTPase Rab11, and the Rab7 effector RILP regulate intracellular trafficking of the chaperone-mediated autophagy receptor LAMP2A.Cystinosin-LKG rescues cystine accumulation and decreases apoptosis rate in cystinotic proximal tubular epithelial cells.
P2860
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P2860
Upregulation of the Rab27a-dependent trafficking and secretory mechanisms improves lysosomal transport, alleviates endoplasmic reticulum stress, and reduces lysosome overload in cystinosis.
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Upregulation of the Rab27a-dep ...... sosome overload in cystinosis.
@ast
Upregulation of the Rab27a-dep ...... sosome overload in cystinosis.
@en
type
label
Upregulation of the Rab27a-dep ...... sosome overload in cystinosis.
@ast
Upregulation of the Rab27a-dep ...... sosome overload in cystinosis.
@en
prefLabel
Upregulation of the Rab27a-dep ...... sosome overload in cystinosis.
@ast
Upregulation of the Rab27a-dep ...... sosome overload in cystinosis.
@en
P2860
P50
P356
P1476
Upregulation of the Rab27a-dep ...... sosome overload in cystinosis.
@en
P2093
Jennifer L Johnson
Jlenia Monfregola
P2860
P304
P356
10.1128/MCB.00417-13
P407
P577
2013-05-28T00:00:00Z