Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis. - Wikidata - wikimedia - TriplyDB

Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.

Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.

http://www.wikidata.org/entity/Q30572690

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FERM domain-containing unconventional myosin VIIA interacts with integrin β5 subunit and regulates αvβ5-mediated cell adhesion and migration Myosins as fundamental components during tumorigenesis: diverse and indispensable Myosin-X and disease Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE.α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.A MAPK-Driven Feedback Loop Suppresses Rac Activity to Promote RhoA-Driven Cancer Cell Invasion The myosin X motor is optimized for movement on actin bundles.Regulated lysosomal exocytosis mediates cancer progression Lgr4 and Lgr5 drive the formation of long actin-rich cytoneme-like membrane protrusions.L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling.miR-600 inhibits cell proliferation, migration and invasion by targeting p53 in mutant p53-expressing human colorectal cancer cell lines.Plasma membrane proteomics of human breast cancer cell lines identifies potential targets for breast cancer diagnosis and treatment.Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasis.Non-muscle myosins in tumor progression, cancer cell invasion, and metastasis.Flipping the switch: integrin switching provides metastatic competence Flightless I interacts with NMMIIA to promote cell extension formation, which enables collagen remodeling.SOST Inhibits Prostate Cancer Invasion.BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function.Ki-67 expression in luminal type breast cancer and its association with the clinicopathology of the cancer Mutant p53 induces EZH2 expression and promotes epithelial-mesenchymal transition by disrupting p68-Drosha complex assembly and attenuating miR-26a processing Integrin endosomal signalling suppresses anoikis.Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis MiR-20a-5p represses multi-drug resistance in osteosarcoma by targeting the KIF26B gene MyTH4-FERM myosins have an ancient and conserved role in filopod formation Myosin 1e promotes breast cancer malignancy by enhancing tumor cell proliferation and stimulating tumor cell de-differentiation.Double mutant P53 (N340Q/L344R) promotes hepatocarcinogenesis through upregulation of Pim1 mediated by PKM2 and LncRNA CUDR Integrin traffic - the update.New insight on the biological role of p53 protein as a tumor suppressor: re-evaluation of its clinical significance in triple-negative breast cancer.p53 regulates cytoskeleton remodeling to suppress tumor progression.FiloQuant reveals increased filopodia density during breast cancer progression.Signaling filopodia in vertebrate embryonic development.Specific Myosins Control Actin Organization, Cell Morphology, and Migration in Prostate Cancer Cells.Correlation of Forkhead Box c2 with subtypes and invasive ability of invasive breast cancer.MyTH4-FERM myosins in the assembly and maintenance of actin-based protrusions.Functions of the Tumor Suppressors p53 and Rb in Actin Cytoskeleton Remodeling Identification of a novel p53 target, COL17A1, that inhibits breast cancer cell migration and invasion Myosin Va plays essential roles in maintaining normal mitosis, enhancing tumor cell motility and viability.Filopodia formation and endosome clustering induced by mutant plus-end-directed myosin VI.Contrast-Enhanced Ultrasonography Features of Breast Malignancies with Different Sizes: Correlation with Prognostic Factors Johanna Ivaska: Finding opposing forces in integrins

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P2860

Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.

http://www.wikidata.org/entity/Q30572690

description

2014 nî lūn-bûn

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2014 թուականի Մարտին հրատարակուած գիտական յօդուած

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2014 թվականի մարտին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Mutant p53-associated myosin-X ...... ancer invasion and metastasis.

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Mutant p53-associated myosin-X ...... ancer invasion and metastasis.

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type

label

Mutant p53-associated myosin-X ...... ancer invasion and metastasis.

@ast

Mutant p53-associated myosin-X ...... ancer invasion and metastasis.

@en

prefLabel

Mutant p53-associated myosin-X ...... ancer invasion and metastasis.

@ast

Mutant p53-associated myosin-X ...... ancer invasion and metastasis.

@en

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Journal of Clinical Investigation

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Mutant p53-associated myosin-X ...... cancer invasion and metastasis

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Antti Arjonen

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Bryan W Miller

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Elina Mattila

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Gunilla Högnäs

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Pegah Rouhi

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Pekka Taimen

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Reetta Virtakoivu

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Riina Kaukonen

http://www.w3.org/2001/XMLSchema#string

Yihai Cao

http://www.w3.org/2001/XMLSchema#string

P2860

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of beta1-integrins.

Thermodynamic stability of wild-type and mutant p53 core domain

Independent prognostic value of fascin immunoreactivity in stage I nonsmall cell lung cancer

Filopodia and adhesion in cancer cell motility

The mechanism of pentabromopseudilin inhibition of myosin motor activity

Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

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1069-1082

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10.1172/JCI67280

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3

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124

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Jennifer P. Morton

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2014-03-01T00:00:00Z

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24487586

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3934176

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