Second cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6 - Wikidata - wikimedia - TriplyDB

Second cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6

Second cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6

http://www.wikidata.org/entity/Q30573147

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The molecular pathogenesis of migraine: new developments and opportunities Autophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?The unstable repeats--three evolving faces of neurological disease An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron The first knockin mouse model of episodic ataxia type 2 Cellular commitment in the developing cerebellum Molecular mechanism of Spinocerebellar Ataxia type 6: glutamine repeat disorder, channelopathy and transcriptional dysregulation. The multifaceted aspects of a single mutation.The role for alterations in neuronal activity in the pathogenesis of polyglutamine repeat disorders.DnaJ-1 and karyopherin α3 suppress degeneration in a new Drosophila model of Spinocerebellar Ataxia Type 6.Genetic Evidence for Possible Involvement of the Calcium Channel Gene CACNA1A in Autism Pathogenesis in Chinese Han Population.Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model Rapid Onset of Motor Deficits in a Mouse Model of Spinocerebellar Ataxia Type 6 Precedes Late Cerebellar Degeneration DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia.4-aminopyridine reverses ataxia and cerebellar firing deficiency in a mouse model of spinocerebellar ataxia type 6.RNA-binding proteins impacting on internal initiation of translation.Polyglutamine length-dependent toxicity from α1ACT in Drosophila models of spinocerebellar ataxia type 6.Using RNA inverse folding to identify IRES-like structural subdomains.The expanding role for chromatin and transcription in polyglutamine disease.The autosomal dominant spinocerebellar ataxias: emerging mechanistic themes suggest pervasive Purkinje cell vulnerability.Genetic landscape remodelling in spinocerebellar ataxias: the influence of next-generation sequencing.Alternative splicing in the C-terminal tail of Cav2.1 is essential for preventing a neurological disease in mice.Modulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.Mammalian Polycistronic mRNAs and Disease.Transcriptional regulation of voltage-gated Ca2+ channels.Designing synthetic RNAs to determine the relevance of structural motifs in picornavirus IRES elements.Comparative genetics. Systematic discovery of cap-independent translation sequences in human and viral genomes.Toward a systematic understanding of translational regulatory elements in human and viruses Downregulation of the Wnt/β-catenin signaling pathway by Cacnb4.Sequence features of viral and human Internal Ribosome Entry Sites predictive of their activity.Revelations from a bicistronic calcium channel gene.Cerebellar Atrophy and Changes in Cytokines Associated with the CACNA1A R583Q Mutation in a Russian Familial Hemiplegic Migraine Type 1 Family.Dystonia and ataxia progression in spinocerebellar ataxias.Bicistronic CACNA1A Gene Expression in Neurons Derived from Spinocerebellar Ataxia Type 6 Patient-Induced Pluripotent Stem Cells.Insights into Structural and Mechanistic Features of Viral IRES Elements.Local Estrogen Synthesis Regulates Parallel Fiber-Purkinje Cell Neurotransmission within the Cerebellar Cortex.Polyglutamine spinocerebellar ataxias - from genes to potential treatments.Self-Organized Cerebellar Tissue from Human Pluripotent Stem Cells and Disease Modeling with Patient-Derived iPSCs.Transient cerebellar alterations during development prior to obvious motor phenotype in a mouse model of spinocerebellar ataxia type 6.Targeting the CACNA1A IRES as a Treatment for Spinocerebellar Ataxia Type 6.The central role of DNA damage and repair in CAG repeat diseases.

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Second cistron in CACNA1A gene encodes a transcription factor mediating cerebellar development and SCA6

http://www.wikidata.org/entity/Q30573147

description

2013 nî lūn-bûn

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2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2013年の論文

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2013年学术文章

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2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

@zh-sg

2013年學術文章

@yue

name

Second cistron in CACNA1A gene ...... erebellar development and SCA6

@ast

Second cistron in CACNA1A gene ...... erebellar development and SCA6

@en

type

label

Second cistron in CACNA1A gene ...... erebellar development and SCA6

@ast

Second cistron in CACNA1A gene ...... erebellar development and SCA6

@en

prefLabel

Second cistron in CACNA1A gene ...... erebellar development and SCA6

@ast

Second cistron in CACNA1A gene ...... erebellar development and SCA6

@en

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J.CELL.2013.05.059

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P1476

Second cistron in CACNA1A gene ...... erebellar development and SCA6

@en

P2093

Ann C Palmenberg

http://www.w3.org/2001/XMLSchema#string

Christian Hansel

http://www.w3.org/2001/XMLSchema#string

Christopher M Gomez

http://www.w3.org/2001/XMLSchema#string

Haipeng Zhu

http://www.w3.org/2001/XMLSchema#string

Jun Wang

http://www.w3.org/2001/XMLSchema#string

Lorenzo Rinaldo

http://www.w3.org/2001/XMLSchema#string

Xiaofei Du

http://www.w3.org/2001/XMLSchema#string

P2860

Identification and characterization of a novel cell cycle-regulated internal ribosome entry site

C-termini of P/Q-type Ca2+ channel alpha1A subunits translocate to nuclei and promote polyglutamine-mediated toxicity

Mfold web server for nucleic acid folding and hybridization prediction

KLF15 Is a transcriptional regulator of the human 17beta-hydroxysteroid dehydrogenase type 5 gene. A potential link between regulation of testosterone production and fat stores in women

Searching for IRES

Bridging IRES elements in mRNAs to the eukaryotic translation apparatus

Interaction of PRMT1 with BTG/TOB proteins in cell signalling: molecular analysis and functional aspects

The p36 isoform of BAG-1 is translated by internal ribosome entry following heat shock

Short-term synaptic plasticity

Voltage-gated calcium channels

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118-133

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scholarly article

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10.1016/J.CELL.2013.05.059

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1

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154

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Kay-Marie Lamar

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2013-07-01T00:00:00Z

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245537784

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23827678

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3939801

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