The diversity of the lipoxygenase family. Many sequence data but little information on biological significance.
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Evidence that arachidonate 15-lipoxygenase 2 is a negative cell cycle regulator in normal prostate epithelial cells12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress12/15-lipoxygenase contributes to platelet-derived growth factor-induced activation of signal transducer and activator of transcription 3Dietary polyunsaturated fatty acids and inflammation: the role of phospholipid biosynthesisIntegrated application of transcriptomics and metabolomics yields insights into population-asynchronous ovary development in Coilia nasus.Inhibition of oxygen-induced ischemic retinal neovascularization with adenoviral 15-lipoxygenase-1 gene transfer via up-regulation of PPAR-γ and down-regulation of VEGFR-2 expressionThe 1.85 Å Structure of an 8 R -Lipoxygenase Suggests a General Model for Lipoxygenase Product SpecificityA Covalent Linker Allows for Membrane Targeting of an Oxylipin Biosynthetic Complex † ‡Functional and pathological roles of the 12- and 15-lipoxygenasesBioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen speciesPositional- and stereo-selectivity of fatty acid oxygenation catalysed by mouse (12S)-lipoxygenase isoenzymesEicosanoids participate in the regulation of cardiac glucose transport by contribution to a rearrangement of actin cytoskeletal elementsEnzymic characterization of epidermis-derived 12-lipoxygenase isoenzymesCharacterization of the lipoxygenase (LOX) gene family in the Chinese white pear (Pyrus bretschneideri) and comparison with other members of the RosaceaeBacterial lipoxygenases, a new subfamily of enzymes? A phylogenetic approach.Molecular dynamics simulation of mammalian 15S-lipoxygenase with AMBER force field.Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3The N-terminal domain of the reticulocyte-type 15-lipoxygenase is not essential for enzymatic activity but contains determinants for membrane binding.Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.Data on expression of lipoxygenases-5 and -12 in the normal and acetaminophen-damaged liver.Structural basis for lipoxygenase specificity. Conversion of the human leukocyte 5-lipoxygenase to a 15-lipoxygenating enzyme species by site-directed mutagenesis.Mutagenesis and modelling of linoleate-binding to pea seed lipoxygenase.Identification of lipoxygenase inhibitory peptides from beta-casein by using SPOT synthesis.Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease.Thrombin-activated human platelets acutely generate oxidized docosahexaenoic-acid-containing phospholipids via 12-lipoxygenase.Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrateMetabolic and Biochemical Stressors in Diabetic Cardiomyopathy.Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation.12-Lipoxygenase overexpression in rodent NG108-15 cells enhances membrane excitability by inhibiting M-type K+ channels.Location, location, location: compartmentalization of early events in leukotriene biosynthesis.Regulation of inflammation by selenium and selenoproteins: impact on eicosanoid biosynthesis.15-lipoxygenase-1: a prooxidant enzyme.Role of 12-lipoxygenase in regulation of ovarian cancer cell proliferation and survival.Role of 15-lipoxygenase/15-hydroxyeicosatetraenoic acid in hypoxia-induced pulmonary hypertension.Ratio of pro-resolving and pro-inflammatory lipid mediator precursors as potential markers for aggressive periodontitis.Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout mice.Absence of 12/15 lipoxygenase reduces brain oxidative stress in apolipoprotein E-deficient mice.Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of a 12R-LOX-chaperone complex.Antioxidant and anti-inflammatory effects of exercise in diabetic patients.Mechanistic contribution of ubiquitous 15-lipoxygenase-1 expression loss in cancer cells to terminal cell differentiation evasion.
P2860
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P2860
The diversity of the lipoxygenase family. Many sequence data but little information on biological significance.
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The diversity of the lipoxygen ...... on on biological significance.
@ast
The diversity of the lipoxygen ...... on on biological significance.
@en
type
label
The diversity of the lipoxygen ...... on on biological significance.
@ast
The diversity of the lipoxygen ...... on on biological significance.
@en
prefLabel
The diversity of the lipoxygen ...... on on biological significance.
@ast
The diversity of the lipoxygen ...... on on biological significance.
@en
P1433
P1476
The diversity of the lipoxygen ...... on on biological significance.
@en
P2093
P356
10.1016/S0014-5793(99)00396-8
P407
P577
1999-04-01T00:00:00Z