S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding.
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The role of titin and extracellular matrix remodelling in heart failure with preserved ejection fractionTitin, a Central Mediator for Hypertrophic Signaling, Exercise-Induced Mechanosignaling and Skeletal Muscle RemodelingThe Measurement of Reversible Redox Dependent Post-translational Modifications and Their Regulation of Mitochondrial and Skeletal Muscle FunctionHeart failure with preserved ejection fraction: mechanisms, clinical features, and therapiesPathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implicationsProtein S-sulfenylation is a fleeting molecular switch that regulates non-enzymatic oxidative foldingMechanical Deformation Accelerates Protein Ageing.Mechanical forces regulate the reactivity of a thioester bond in a bacterial adhesinResidue Modification and Mass Spectrometry for the Investigation of Structural and Metalation Properties of Metallothionein and Cysteine-Rich ProteinsAltered thiol chemistry in human amyotrophic lateral sclerosis-linked mutants of superoxide dismutase 1Force is a signal that cells cannot ignore.Peripartum cardiomyopathy and dilated cardiomyopathy: different at heart.Emerging importance of oxidative stress in regulating striated muscle elasticity.A novel strategy for utilizing voice coil servoactuators in tensile tests of low volume protein hydrogels.Dynamics of equilibrium folding and unfolding transitions of titin immunoglobulin domain under constant forces.Site-Specific Proteomic Mapping Identifies Selectively Modified Regulatory Cysteine Residues in Functionally Distinct Protein Networks.CnaA domains in bacterial pili are efficient dissipaters of large mechanical shocks.Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion.Site-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics.Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death.Pathomechanisms in heart failure: the contractile connection.How do disordered regions achieve comparable functions to structured domains?The structure and function of cell membranes examined by atomic force microscopy and single-molecule force spectroscopy.Titin mutations: the fall of Goliath.Myocardial reverse remodeling: how far can we rewind?Watching cellular machinery in action, one molecule at a time.Tampering with springs: phosphorylation of titin affecting the mechanical function of cardiomyocytes.A change of heart: oxidative stress in governing muscle function?Positive Regulation of Interleukin-1β Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation.A HaloTag Anchored Ruler for Week-Long Studies of Protein Dynamics.Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function.Titin domains progressively unfolded by force are homogenously distributed along the molecule.Redox-sensitive residue in the actin-binding interface of myosinTailoring protein nanomechanics with chemical reactivity.Molecular basis of the mechanical hierarchy in myomesin dimers for sarcomere integrity.Mechanochemical evolution of the giant muscle protein titin as inferred from resurrected proteins.Clickable glutathione using tetrazine-alkene bioorthogonal chemistry for detecting protein glutathionylation.Chemical methods for mapping cysteine oxidation.A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation.Disulfide isomerization reactions in titin immunoglobulin domains enable a mode of protein elasticity.
P2860
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P2860
S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
S-glutathionylation of cryptic ...... y by blocking protein folding.
@ast
S-glutathionylation of cryptic ...... y by blocking protein folding.
@en
type
label
S-glutathionylation of cryptic ...... y by blocking protein folding.
@ast
S-glutathionylation of cryptic ...... y by blocking protein folding.
@en
prefLabel
S-glutathionylation of cryptic ...... y by blocking protein folding.
@ast
S-glutathionylation of cryptic ...... y by blocking protein folding.
@en
P2093
P2860
P1433
P1476
S-glutathionylation of cryptic ...... y by blocking protein folding.
@en
P2093
Chad M Warren
Edward Eckels
Jaime Andrés Rivas-Pardo
Julio M Fernández
Nazha Hamdani
Pallav Kosuri
R John Solaro
Wolfgang A Linke
P2860
P304
P356
10.1016/J.CELL.2014.01.056
P407
P577
2014-03-01T00:00:00Z