Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
about
Subunit composition of a DEG/ENaC mechanosensory channel of Caenorhabditis elegans.Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons.Two aspects of ASIC function: Synaptic plasticity and neuronal injury.The comprehensive analysis of DEG/ENaC subunits in Hydra reveals a large variety of peptide-gated channels, potentially involved in neuromuscular transmission.The Human Acid-Sensing Ion Channel ASIC1a: Evidence for a Homotetrameric Assembly State at the Cell Surface.Extracellular Subunit Interactions Control Transitions between Functional States of Acid-sensing Ion Channel 1a.ASIC1a Deficient Mice Show Unaltered Neurodegeneration in the Subacute MPTP Model of Parkinson Disease.ASIC subunit ratio and differential surface trafficking in the brain.Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling.PIP Water Transport and Its pH Dependence Are Regulated by Tetramer Stoichiometry.Photoactivation of an Acid-Sensitive Ion Channel Associated with Vision and Pain.Single-molecule methods to study membrane receptor oligomerization.The Single-Molecule Approach to Membrane Protein Stoichiometry.The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na(+) channel (ENaC): IUPHAR Review 19.Manipulation of Subunit Stoichiometry in Heteromeric Membrane Proteins.Deactivation kinetics of acid-sensing ion channel 1a are strongly pH-sensitive.Conformational dynamics and role of the acidic pocket in ASIC pH-dependent gating.Functional and pharmacological characterization of two different ASIC1a/2a heteromers reveals their sensitivity to the spider toxin PcTx1.Glioblastoma cancer stem cell lines express functional acid sensing ion channels ASIC1a and ASIC3.Identification of a cono-RFamide from the venom of Conus textile that targets ASIC3 and enhances muscle pain.Genetic mapping of ASIC4 and contrasting phenotype to ASIC1a in modulating innate fear and anxiety.Acid-sensing ion channels are tuned to follow high-frequency stimuli.Altered Expression Pattern of Acid-Sensing Ion Channel Isoforms in Piriform Cortex After Seizures.New techniques, applications and perspectives in neuropeptide research.NS383 Selectively Inhibits Acid-Sensing Ion Channels Containing 1a and 3 Subunits to Reverse Inflammatory and Neuropathic Hyperalgesia in Rats.The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel.Role of acid-sensing ion channels in hypoxia- and hypercapnia-induced ventilatory responses.Dual actions of Psalmotoxin at ASIC1a and ASIC2a heteromeric channels (ASIC1a/2a).
P2860
Q27318584-73D4D176-CCCB-4C8E-BF50-47A41FC7D422Q27349717-4987CCC8-CC5F-4DC1-9F76-74C377070208Q28082631-CD5A4B5C-0D60-4D3C-9BF6-34E6CB927025Q34416680-A88E518C-1DCB-44B7-9846-90B01B074A3CQ35739738-65517435-EEB1-4627-9F77-35E7932467FCQ35859520-1CFC3426-ECA9-4498-BCAF-3D16E4D4E768Q36184308-DE6C73E4-ECB1-49B0-9D06-C337A72425E7Q36446204-5BFE601C-CFED-47D4-8A67-AD67F4513B24Q36594632-39DBF406-8A64-4302-AC2F-F5233BF85B32Q36753664-0C379F9B-AA11-4731-AA09-279CF871F2BAQ37488937-5CCD8EB2-3469-44AB-8918-07A0CBF46FB3Q38292973-9844E0AC-041F-4201-BA97-0A6B580F8814Q38766717-DFBBBC64-3827-4C04-A054-EAC2975FEC22Q38859500-0BF3733F-B57E-441F-BAD1-4F497A4CE257Q40819683-BA1B6AC5-9994-4F96-B1C2-A239E71040B2Q41710090-8FA7D14B-EACB-4E35-9AC0-1C15608B80D0Q42257199-835BB3F0-5EF7-4E09-9F11-5C620EF7E80AQ42269220-65ACB77E-6FAF-470B-88CF-7F18FC772CE8Q42652751-528D85D6-F396-41BF-95E9-557A363CA964Q43100941-70122568-99D1-4ADE-AFC4-24987044D6AEQ47723272-05868195-000F-45D5-B5AE-FF72A286905FQ48062340-6B279B5D-2962-4C50-9657-4DF728DC2873Q48295387-292F45AC-EA6C-48D0-A657-CB0864707553Q50036098-C72D5747-1F2F-4698-AE43-D27D1B570CB1Q51739932-196B0AB8-60B0-4B01-92FB-EC5C3575C583Q52325871-E8DEF079-F3BD-41FB-BC5F-F528ECC5C6FBQ52688345-0B06FF5F-F379-41DB-B169-E3E36C1C967EQ54985611-90A7EC60-2BB8-4978-9DC3-B274AD4D39DD
P2860
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
description
2014 nî lūn-bûn
@nan
2014 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
@ast
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
@en
type
label
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
@ast
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
@en
prefLabel
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
@ast
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
@en
P2093
P2860
P356
P1476
Acid-sensing ion channel (ASIC) 1a/2a heteromers have a flexible 2:1/1:2 stoichiometry
@en
P2093
Georg Polleichtner
Katrin Augustinowski
Maximilian H Ulbrich
Tudor Bartoi
P2860
P304
P356
10.1073/PNAS.1324060111
P407
P577
2014-05-20T00:00:00Z