GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug - Wikidata - wikimedia - TriplyDB

GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug

GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug

http://www.wikidata.org/entity/Q30583575

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Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells Interleukin-23 promotes the epithelial-mesenchymal transition of oesophageal carcinoma cells via the Wnt/β-catenin pathway Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis.A MicroRNA/Ubiquitin Ligase Feedback Loop Regulates Slug-Mediated Invasion in Breast Cancer.Pellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination.Analysis of epithelial-mesenchymal transition markers in psoriatic epidermal keratinocytes.Lnc-CC3 increases metastasis in cervical cancer by increasing Slug expression Regulation of the protein stability of EMT transcription factors Targeting cancer by binding iron: Dissecting cellular signaling pathways PIK3CA(H1047R) Accelerates and Enhances KRAS(G12D)-Driven Lung Tumorigenesis.MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma.Cycloheximide Chase Analysis of Protein Degradation in Saccharomyces cerevisiae The SIRT2 Deacetylase Stabilizes Slug to Control Malignancy of Basal-like Breast Cancer.The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells.Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer.Long non-coding RNA linc00261 suppresses gastric cancer progression via promoting Slug degradation.Cordycepin induces human lung cancer cell apoptosis by inhibiting nitric oxide mediated ERK/Slug signaling pathway.Adenovirus-mediated TIPE2 overexpression inhibits gastric cancer metastasis via reversal of epithelial-mesenchymal transition.MicroRNAs contribution in tumor microenvironment of esophageal cancer.miR-205 promotes epithelial-mesenchymal transition by targeting AKT signaling in endometrial cancer cells.Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.PSAT1 regulates cyclin D1 degradation and sustains proliferation of non-small cell lung cancer cells.Targeting protein kinase-b3 (akt3) signaling in melanoma.ZO-2, a tight junction protein involved in gene expression, proliferation, apoptosis, and cell size regulation.Intranuclear accumulation of galectin-3 is an independent prognostic factor for patients with distal cholangiocarcinoma.Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells.ERp29 controls invasion and metastasis of gastric carcinoma by inhibition of epithelial-mesenchymal transition via PI3K/Aktsignaling pathway.The structure of the human ABC transporter ABCG2 reveals a novel mechanism for drug extrusion.Analysis of Protein Stability by the Cycloheximide Chase Assay.Deletion and downregulation of MTAP contribute to the motility of esophageal squamous carcinoma cells.Cellular inhibitor of apoptosis protein 2 promotes the epithelial-mesenchymal transition in triple-negative breast cancer cells through activation of the AKT signaling pathway.Human Primary Epithelial Cells Acquire an Epithelial-Mesenchymal-Transition Phenotype during Long-Term Infection by the Oral Opportunistic Pathogen, Porphyromonas gingivalis.Post-transcriptional Regulation of Genes Related to Biological Behaviors of Gastric Cancer by Long Noncoding RNAs and MicroRNAs.PIPKIγ and talin couple phosphoinositide and adhesion signaling to control the epithelial to mesenchymal transition.CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression.miR-203a regulates proliferation, migration, and apoptosis by targeting glycogen synthase kinase-3β in human renal cell carcinoma.Frequently rearranged and overexpressed δ-catenin is responsible for low sensitivity of prostate cancer cells to androgen receptor and β-catenin antagonists.Cypripedin diminishes an epithelial-to-mesenchymal transition in non-small cell lung cancer cells through suppression of Akt/GSK-3β signalling.Huntingtin-Interacting Protein-1 Is an Early-Stage Prognostic Biomarker of Lung Adenocarcinoma and Suppresses Metastasis via Akt-mediated Epithelial-Mesenchymal Transition.CHIP functions as an oncogene by promoting colorectal cancer metastasis via activation of MAPK and AKT signaling and suppression of E-cadherin.

P2860

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P2860

GSK3β controls epithelial-mesenchymal transition and tumor metastasis by CHIP-mediated degradation of Slug

http://www.wikidata.org/entity/Q30583575

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2013 nî lūn-bûn

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2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2013 թվականի հուլիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

GSK3β controls epithelial-mese ...... P-mediated degradation of Slug

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GSK3β controls epithelial-mese ...... P-mediated degradation of Slug

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GSK3β controls epithelial-mese ...... P-mediated degradation of Slug

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GSK3β controls epithelial-mese ...... P-mediated degradation of Slug

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GSK3β controls epithelial-mese ...... P-mediated degradation of Slug

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GSK3β controls epithelial-mese ...... P-mediated degradation of Slug

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GSK3β controls epithelial-mese ...... P-mediated degradation of Slug

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C-Y Chen

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P-C Yang

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S-H Kao

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S-P Wang

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T-M Hong

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W-L Wang

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Y-J Chen

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Y-T Wang

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Y-Y Wu

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P2860

Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

The SLUG zinc-finger protein represses E-cadherin in breast cancer

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7

Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug, and MAPK

Cancer invasion and the microenvironment: plasticity and reciprocity

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3172-3182

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10.1038/ONC.2013.279

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24

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33

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Alexey I. Nesvizhskii

Yih-leong Chang

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2013-07-15T00:00:00Z

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1024347246

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23851495

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4096338

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