PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.
about
Real-time monitoring of cell protrusion dynamics by impedance responses.A novel small-molecule MRCK inhibitor blocks cancer cell invasionMyotonic dystrophy kinase-related Cdc42-binding kinases (MRCK), the ROCK-like effectors of Cdc42 and Rac1.Serine/Threonine Kinase 3-Phosphoinositide-Dependent Protein Kinase-1 (PDK1) as a Key Regulator of Cell Migration and Cancer Dissemination.MRCKα is activated by caspase cleavage to assemble an apical actin ring for epithelial cell extrusion.PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway.
P2860
PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
PDK1-mediated activation of MR ...... n and lamellipodia retraction.
@ast
PDK1-mediated activation of MR ...... n and lamellipodia retraction.
@en
type
label
PDK1-mediated activation of MR ...... n and lamellipodia retraction.
@ast
PDK1-mediated activation of MR ...... n and lamellipodia retraction.
@en
prefLabel
PDK1-mediated activation of MR ...... n and lamellipodia retraction.
@ast
PDK1-mediated activation of MR ...... n and lamellipodia retraction.
@en
P2093
P2860
P50
P356
P1476
PDK1-mediated activation of MR ...... on and lamellipodia retraction
@en
P2093
Federica Chianale
Luca Primo
Roberto Sessa
Thomas Leung
P2860
P304
P356
10.1083/JCB.201312090
P407
P577
2014-08-01T00:00:00Z